ID K4L7Z6_9FIRM Unreviewed; 607 AA.
AC K4L7Z6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Polysaccharide biosynthesis protein CapD {ECO:0000313|EMBL:AFV06701.1};
DE EC=4.2.1.- {ECO:0000313|EMBL:AFV06701.1};
GN ORFNames=DCF50_p2698 {ECO:0000313|EMBL:AFV06701.1};
OS Dehalobacter sp. CF.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Desulfitobacteriaceae;
OC Dehalobacter.
OX NCBI_TaxID=1131462 {ECO:0000313|EMBL:AFV06701.1, ECO:0000313|Proteomes:UP000000482};
RN [1] {ECO:0000313|EMBL:AFV06701.1, ECO:0000313|Proteomes:UP000000482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CF {ECO:0000313|EMBL:AFV06701.1};
RX PubMed=23284863; DOI=10.1371/journal.pone.0052038;
RA Tang S., Gong Y., Edwards E.A.;
RT "Semi-automatic in silico gap closure enabled de novo assembly of two
RT dehalobacter genomes from metagenomic data.";
RL PLoS ONE 7:E52038-E52038(2012).
CC -!- SIMILARITY: Belongs to the polysaccharide synthase family.
CC {ECO:0000256|ARBA:ARBA00007430}.
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DR EMBL; CP003870; AFV06701.1; -; Genomic_DNA.
DR AlphaFoldDB; K4L7Z6; -.
DR STRING; 1131462.DCF50_p2698; -.
DR KEGG; dec:DCF50_p2698; -.
DR PATRIC; fig|1131462.4.peg.2726; -.
DR eggNOG; COG1086; Bacteria.
DR HOGENOM; CLU_013560_5_2_9; -.
DR Proteomes; UP000000482; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR CDD; cd05237; UDP_invert_4-6DH_SDR_e; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR003869; Polysac_CapD-like.
DR PANTHER; PTHR43318:SF1; POLYSACCHARIDE BIOSYNTHESIS PROTEIN EPSC-RELATED; 1.
DR PANTHER; PTHR43318; UDP-N-ACETYLGLUCOSAMINE 4,6-DEHYDRATASE; 1.
DR Pfam; PF13727; CoA_binding_3; 1.
DR Pfam; PF02719; Polysacc_synt_2; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:AFV06701.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000482};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 98..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 278..557
FT /note="Polysaccharide biosynthesis protein CapD-like"
FT /evidence="ECO:0000259|Pfam:PF02719"
SQ SEQUENCE 607 AA; 67356 MW; 69D59231DA1C4543 CRC64;
MLTDAILINL ALFLSFYLRL SEEADLQVEF VKYLGTYLNA AIVSTFVLIV VFHFFGLYKN
IWRYASVREL LSIVYAVTVG AALTVMVVYF ISPLRLPHSV SVYFWLMLIV LIGGLRFSQR
MRQENAIFAV SNRSQRKVLI IGAGDAGVLA LRELKKRDFQ EGVPVGFIDD SKSKINLHVQ
GFPVLGSRDD IRRIVEDYAV DEIIIAIPSA DGETVREIVE ICKETRAVLK IMPGVYDILS
GKITVSSLRE VQVEDLLGRE QVSVDLEEVA GYLKNQVVLV TGAGGSIGSE LCRQIVKFFP
SKLILAGHGE NCIFDIEQEL KNSPIVTEIF DIKDAGKVNL VFEKYKPYVV FHAAAHKHVP
LMEVNPEEAL KNNVMGTSNL AAAADKNGVR TFVLISTDKA VNPTSIMGAS KRMAEMVIQD
YDKRSETKFV AVRFGNVLGS RGSVIPTFKK QIMAGGPVTV TDPRMTRYFM TIPEASQLVI
QAGAMASGGE IFILDMGKPV KIVDLAKDLI RLSGFEPGKD IQIEFTGVRP GEKLFEEILT
SEEGTTATKH KRIFVARPNH IDHEAIEGLV QKIRERGSYM DREEINTSIR TLLPDFGKTI
NTQAAQS
//
