ID K4LB54_SALSA Unreviewed; 178 AA.
AC K4LB54;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=IFNd {ECO:0000313|EMBL:AFV08801.1, ECO:0000313|RefSeq:NP_001266021.1};
GN Name=LOC101448041 {ECO:0000313|RefSeq:NP_001266021.1};
OS Salmo salar (Atlantic salmon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes;
OC Salmonidae; Salmoninae; Salmo.
OX NCBI_TaxID=8030 {ECO:0000313|EMBL:AFV08801.1};
RN [1] {ECO:0000313|EMBL:AFV08801.1, ECO:0000313|RefSeq:NP_001266021.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Head kidney {ECO:0000313|EMBL:AFV08801.1};
RX PubMed=23169587; DOI=10.4049/jimmunol.1201188;
RA Svingerud T., Solstad T., Sun B., Nyrud M.L., Kileng O.,
RA Greiner-Tollersrud L., Robertsen B.;
RT "Atlantic salmon type I IFN subtypes show differences in antiviral activity
RT and cell-dependent expression: evidence for high IFNb/IFNc-producing cells
RT in fish lymphoid tissues.";
RL J. Immunol. 189:5912-5923(2012).
RN [2] {ECO:0000313|RefSeq:NP_001266021.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the alpha/beta interferon family.
CC {ECO:0000256|RuleBase:RU000436}.
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DR EMBL; JX524151; AFV08801.1; -; mRNA.
DR RefSeq; NP_001266021.1; NM_001279092.1.
DR STRING; 8030.ENSSSAP00000070149; -.
DR PaxDb; 8030-ENSSSAP00000070149; -.
DR GeneID; 101448041; -.
DR KEGG; sasa:101448041; -.
DR OrthoDB; 3847678at2759; -.
DR Proteomes; UP000087266; Chromosome ssa19.
DR GO; GO:0005615; C:extracellular space; IEA:UniProtKB-KW.
DR GO; GO:0005125; F:cytokine activity; IEA:UniProtKB-KW.
DR GO; GO:0005126; F:cytokine receptor binding; IEA:InterPro.
DR GO; GO:0051607; P:defense response to virus; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1250.10; -; 1.
DR InterPro; IPR009079; 4_helix_cytokine-like_core.
DR InterPro; IPR000471; Interferon_alpha/beta/delta.
DR PANTHER; PTHR11691:SF37; INTERFERON OMEGA-1; 1.
DR PANTHER; PTHR11691; TYPE I INTERFERON; 1.
DR Pfam; PF00143; Interferon; 1.
DR SMART; SM00076; IFabd; 1.
DR SUPFAM; SSF47266; 4-helical cytokines; 1.
PE 2: Evidence at transcript level;
KW Antiviral defense {ECO:0000256|ARBA:ARBA00023118,
KW ECO:0000256|RuleBase:RU000436}; Cytokine {ECO:0000256|RuleBase:RU000436};
KW Reference proteome {ECO:0000313|Proteomes:UP000087266};
KW Signal {ECO:0000256|SAM:SignalP, ECO:0000313|RefSeq:NP_001266021.1}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..178
FT /evidence="ECO:0000256|SAM:SignalP,
FT ECO:0000313|RefSeq:NP_001266021.1"
FT /id="PRO_5009732510"
SQ SEQUENCE 178 AA; 20653 MW; 39DE10AC5D636D39 CRC64;
MHRPTKSLLI CLFLTMCDGF SMGCRWMDDH KFIQHSETLM NLLNIMGGEF TTDSVDVPFP
EDLYKQAEYL PTDDTIWFIL QTLDKIAELF DGEPDSVWNE KKVEIFLSVL NSQSDGLQSC
VTAQKKNSKN LQMYFKRLHN QVLKRMAYSA HAWELVRKEV RTHLMRLVLL GSATENSI
//
