ID K4LE80_THEPS Unreviewed; 703 AA.
AC K4LE80;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Sigma54 specific transcriptional regulator {ECO:0000313|EMBL:AFV10382.1};
GN OrderedLocusNames=Tph_c01340 {ECO:0000313|EMBL:AFV10382.1};
OS Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 26808 / PB).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermacetogenium.
OX NCBI_TaxID=1089553 {ECO:0000313|EMBL:AFV10382.1, ECO:0000313|Proteomes:UP000000467};
RN [1] {ECO:0000313|EMBL:AFV10382.1, ECO:0000313|Proteomes:UP000000467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-254 / DSM 26808 / PB
RC {ECO:0000313|Proteomes:UP000000467};
RX PubMed=23259483; DOI=10.1186/1471-2164-13-723;
RA Oehler D., Poehlein A., Leimbach A., Muller N., Daniel R., Gottschalk G.,
RA Schink B.;
RT "Genome-guided analysis of physiological and morphological traits of the
RT fermentative acetate oxidizer Thermacetogenium phaeum.";
RL BMC Genomics 13:723-723(2012).
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DR EMBL; CP003732; AFV10382.1; -; Genomic_DNA.
DR AlphaFoldDB; K4LE80; -.
DR STRING; 1089553.Tph_c01340; -.
DR KEGG; tpz:Tph_c01340; -.
DR eggNOG; COG3829; Bacteria.
DR HOGENOM; CLU_000445_8_12_9; -.
DR Proteomes; UP000000467; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR PANTHER; PTHR32071:SF57; SIGMA L-DEPENDENT TRANSCRIPTIONAL REGULATOR YQIR-RELATED; 1.
DR PANTHER; PTHR32071; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF13426; PAS_9; 1.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000000467};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 262..342
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 390..619
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000259|PROSITE:PS50045"
SQ SEQUENCE 703 AA; 79588 MW; 3F9B54100F942811 CRC64;
MPFSSVNYSL VDKATHKRIE IRKMTKERWE GILEVKEKFL QNEIGEDELL SCSYLEPEVA
KSWIRSRNYG VDHKRVILRC EAKSKFKEKL KRNEALIKIV KPLREIFKNF VEASGYGFQL
YDKNGLILLG DGEVIKVKNN VTKGLCLKEG IILNEKNIGT NSHSLCALLR RPVQLIGIEN
YWDELANTMA SAAPIIGEDG EVGGVLLLWQ WLVCEPWNEN FQRLFSHMLG LVTSIAVAIE
TQLRLLKSYE ELKIANDSLA MTNRMLETTL SLIDDGIITV DRNGKITCVN QEGAQILNLK
PDDIGRRNIT EFVENTSSFM DLLKKGESAA IEEVVKNKDE NYIISIRPVY TNDKNKQINA
AVLEFSRAKK VNALVTSRSG AAASFSFDDI VGVSEAITRA KEKAKRFAGC KENILIIGES
GTGKELFAQA IHNWYCPEGP FVAVNCAALP RELIESELFG YEGGSFTGAD RHGRPGKIEL
AEGGTLFLDE IGDMPIELQA VLLRVLEDKK VMRVGGRRFK KVDFRVIAAT NSDLNKMVRE
KLFREDLYYR LSVLRVDIPP LRDRGKDKEI LARYFIEKYC KKIGRKTPQI SPTVRKLIYE
YKWPGNVRQL ENAVIFAINV SKGDVIEVRD LPDEIRSDFS SDHLRICNHN QSNKRVLLLT
EMEKNAIVEA LSETKGNIPR AAELLGISKS TVYRKLKEYN ISV
//
