ID K4LJ07_THEPS Unreviewed; 1376 AA.
AC K4LJ07;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Serine protease/ABC transporter B family protein TagC {ECO:0000313|EMBL:AFV12981.1};
DE EC=3.4.21.- {ECO:0000313|EMBL:AFV12981.1};
GN Name=tagC {ECO:0000313|EMBL:AFV12981.1};
GN OrderedLocusNames=Tph_c28160 {ECO:0000313|EMBL:AFV12981.1};
OS Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 26808 / PB).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermacetogenium.
OX NCBI_TaxID=1089553 {ECO:0000313|EMBL:AFV12981.1, ECO:0000313|Proteomes:UP000000467};
RN [1] {ECO:0000313|EMBL:AFV12981.1, ECO:0000313|Proteomes:UP000000467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-254 / DSM 26808 / PB
RC {ECO:0000313|Proteomes:UP000000467};
RX PubMed=23259483; DOI=10.1186/1471-2164-13-723;
RA Oehler D., Poehlein A., Leimbach A., Muller N., Daniel R., Gottschalk G.,
RA Schink B.;
RT "Genome-guided analysis of physiological and morphological traits of the
RT fermentative acetate oxidizer Thermacetogenium phaeum.";
RL BMC Genomics 13:723-723(2012).
CC -!- SIMILARITY: Belongs to the peptidase S8 family. {ECO:0000256|PROSITE-
CC ProRule:PRU01240}.
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DR EMBL; CP003732; AFV12981.1; -; Genomic_DNA.
DR RefSeq; WP_015051840.1; NZ_KI912609.1.
DR STRING; 1089553.Tph_c28160; -.
DR KEGG; tpz:Tph_c28160; -.
DR eggNOG; COG1404; Bacteria.
DR HOGENOM; CLU_269152_0_0_9; -.
DR OrthoDB; 900053at2; -.
DR Proteomes; UP000000467; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd04842; Peptidases_S8_Kp43_protease; 1.
DR Gene3D; 2.60.120.380; -; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR001119; SLH_dom.
DR InterPro; IPR034058; TagA/B/C/D_pept_dom.
DR PANTHER; PTHR43399; SUBTILISIN-RELATED; 1.
DR PANTHER; PTHR43399:SF4; TK-SUBTILISIN; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR Pfam; PF00395; SLH; 3.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51272; SLH; 3.
DR PROSITE; PS51892; SUBTILASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000000467};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 1192..1255
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 1256..1316
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT DOMAIN 1319..1376
FT /note="SLH"
FT /evidence="ECO:0000259|PROSITE:PS51272"
FT ACT_SITE 232
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 275
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 461
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 1376 AA; 145758 MW; BA08436144E4A9F2 CRC64;
MRRLVVCCAA IVLACFLVVE AIPVFSRQVD THPQETSGAE EGERMVPPEN PVGLFLMPVR
EGEEVPRETL AALGLEKGDP LGRETLLVRL PLNKVEEAKE KGVFLRPYSA ADRLAPGLQG
KKGSEQEIEV LVTLFRSSDR EGFVRKVPEL GGEVLAGLEG EGRVLRLRLP EGALAELAAS
PEVVYVEPAQ EYRFYNERAR DLVGAAFLQA AGFLSPEWMG LSGRGQIIGL ADSGIDAGSP
GDIHPDLQSL PGQMPKVVML KSWAGAATAA DFNGHGTHMA ATVAGTGAAS QGRFKGIAPG
ASIYFQGLLD ESGKLTPPPD LTVLFEPAYA AGVRVHINGW GGEKGGYFGT ASQIDRFLRR
CPDFLAVFSA GNGGPQAGKL TPEAYSKNAL VVGASQSPHP LFNPAQNDAG SISSFSSRGP
TADGRIKPEL YAPGSLISAR SRLADLPSAL SDGYTYLEGT SMAAAVAGGG AALLREFFQR
IEKLAAPSAA LVKAALICGA RTPQGWPNSS GFGILDLGGT VLSLWEKNFR YVDAEEGVAA
GETLSYTFEV KSGESPFKAT LVWTDPGAAP GAEAPLVNNL DLVVRGPEGS EWIGNSFLSD
RPDDVNNVEQ VVIPAPKPGI YTVYVKGKAI TKGVTHRDGR PAQDFALVYG QPLVRDVVTA
AGAQGPVLES GRVLAAAPQQ VRFALNGEVA SWPVSDNGGS LGKVLPGADV YFPPGYASRG
SIYIVGRTFR AVGVQVLDAG GRYLLTEINP EARSGGLYFA PAAEKGVLIN GVPAAGPASV
PPGGGVTAWI NPGSWEIWGA EFSFSAVEGL LGGVDMAKRE LTLIGVEKTY SLAPQAALAY
SDEMVDVDAA DLPFGAAATP CWENLLPGLR VRLVLSPATG EVTYVAARRE LAVGMIAEVD
VMNRRIVLST GRDYTVPVGV SLSLDEKEAH LQDLRPGQYA VGVLLPKTRQ VLSLSAYSSF
LYGQVVYTSL RDGTIYFVDN CGRSGAYRYQ EDTGFYRWGL PAVAAAAEAG CWARLILKPG
ENLIWRLDVA ETTAERREIV AGYDEETGTL ITSQGRYRLT ERTSITKNGY PVAAWDLVPG
EEVALTPFLE GASGEPMLAA VAARTSAGTR APELEVTASW RQGEVVLMGS TTADRLYLYP
EKGDRMSIPV DGKGSFHLSF RPEKEGENFL LVVAVDGGSG GVTGRQLTVS PGTGAVFRDV
AGHWAERAIE ELAARGVLKG YPDGTFRPDD PITRSEFTVL VTTALGLSGG EAELPFADAG
SIPSWARPAV ERAYLHGLVR GSADGCFRPA RKITRAEAAA VLSGALSVIN FREDTPVSPP
HWRDDGAIPT WARPAVERVY AAGVMTGRPN GFFAPGEILT RAEAVSAVRR LLERTP
//
