ID K4LK86_THEPS Unreviewed; 584 AA.
AC K4LK86;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=NADH-quinone oxidoreductase 51 kDa subunit F {ECO:0000313|EMBL:AFV12360.1};
DE EC=1.6.99.5 {ECO:0000313|EMBL:AFV12360.1};
GN Name=nuoF6 {ECO:0000313|EMBL:AFV12360.1};
GN OrderedLocusNames=Tph_c21670 {ECO:0000313|EMBL:AFV12360.1};
OS Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 26808 / PB).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermacetogenium.
OX NCBI_TaxID=1089553 {ECO:0000313|EMBL:AFV12360.1, ECO:0000313|Proteomes:UP000000467};
RN [1] {ECO:0000313|EMBL:AFV12360.1, ECO:0000313|Proteomes:UP000000467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-254 / DSM 26808 / PB
RC {ECO:0000313|Proteomes:UP000000467};
RX PubMed=23259483; DOI=10.1186/1471-2164-13-723;
RA Oehler D., Poehlein A., Leimbach A., Muller N., Daniel R., Gottschalk G.,
RA Schink B.;
RT "Genome-guided analysis of physiological and morphological traits of the
RT fermentative acetate oxidizer Thermacetogenium phaeum.";
RL BMC Genomics 13:723-723(2012).
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; CP003732; AFV12360.1; -; Genomic_DNA.
DR RefSeq; WP_015051235.1; NZ_KI912609.1.
DR AlphaFoldDB; K4LK86; -.
DR STRING; 1089553.Tph_c21670; -.
DR KEGG; tpz:Tph_c21670; -.
DR eggNOG; COG1894; Bacteria.
DR HOGENOM; CLU_014881_3_2_9; -.
DR OrthoDB; 9761899at2; -.
DR Proteomes; UP000000467; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13187; Fer4_9; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000313|EMBL:AFV12360.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000467};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 527..556
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 557..584
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 584 AA; 63567 MW; 94BF9706A430B817 CRC64;
MKIRVGMGSC GIAAGSLKVR ERIVEEIERR GLDLQVQPTG CIGMCHNEPL LDVITGDGRI
FTYGHVTPEL VGEIFEKHII GGVPLTQHLV STSENTNDFL KEQVRVALRN CGEINPECID
DYLDRGGYQA LKQALSSTPE EVIQEIRVSG LRGRGGAGFP TWFKWQAVRQ NPGSVKYVVC
NADEGDPGAF MDRSILEGDP HSVLEGMAIA GYATGAKHGF IYCRAEYPLA VRRLELAIAQ
ARERGLLGRN IFGSGFTFEV AVKEGAGAFV CGEETALIAS LEGERGMPRL KPPYPAQYGY
WGKPTNINNV ETYANVPWII SHGGKAFASM GTEKSKGTKV FALAGKIRRG GLVEVPMGLS
LRDVIFNIGG GIKDNRRFKA VQLGGPSGGC IPESLLDIPV DYESINQTGA IMGSGGMVVM
DDTTCMVDVA RFFLDFTQKE SCGKCVQCRI GTRRMLEILE RICTGEGRPG DEELLEEIAI
QVKEGSLCGL GQSAPNPVLT TLRYFREEYT AHINDKNCPA KQCKALITYR IDPARCQGCG
ACARKCPAKC ISGEKKKPHV IDRELCLKCG NCLDVCHYNA VIIE
//
