ID K4LQP5_THEPS Unreviewed; 525 AA.
AC K4LQP5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE SubName: Full=Molybdopterin containing oxidoreductase YoaE {ECO:0000313|EMBL:AFV10419.1};
DE EC=1.-.-.- {ECO:0000313|EMBL:AFV10419.1};
GN Name=yoaE {ECO:0000313|EMBL:AFV10419.1};
GN OrderedLocusNames=Tph_c01710 {ECO:0000313|EMBL:AFV10419.1};
OS Thermacetogenium phaeum (strain ATCC BAA-254 / DSM 26808 / PB).
OC Bacteria; Bacillota; Clostridia; Thermoanaerobacterales;
OC Thermoanaerobacteraceae; Thermacetogenium.
OX NCBI_TaxID=1089553 {ECO:0000313|EMBL:AFV10419.1, ECO:0000313|Proteomes:UP000000467};
RN [1] {ECO:0000313|EMBL:AFV10419.1, ECO:0000313|Proteomes:UP000000467}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-254 / DSM 26808 / PB
RC {ECO:0000313|Proteomes:UP000000467};
RX PubMed=23259483; DOI=10.1186/1471-2164-13-723;
RA Oehler D., Poehlein A., Leimbach A., Muller N., Daniel R., Gottschalk G.,
RA Schink B.;
RT "Genome-guided analysis of physiological and morphological traits of the
RT fermentative acetate oxidizer Thermacetogenium phaeum.";
RL BMC Genomics 13:723-723(2012).
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR EMBL; CP003732; AFV10419.1; -; Genomic_DNA.
DR RefSeq; WP_015049339.1; NZ_KI912609.1.
DR AlphaFoldDB; K4LQP5; -.
DR STRING; 1089553.Tph_c01710; -.
DR KEGG; tpz:Tph_c01710; -.
DR eggNOG; COG0243; Bacteria.
DR HOGENOM; CLU_000422_13_3_9; -.
DR Proteomes; UP000000467; Chromosome.
DR GO; GO:0018818; F:acetylene hydratase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02781; MopB_CT_Acetylene-hydratase; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR Gene3D; 3.30.2070.10; Formate dehydrogenase/DMSO reductase; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR037949; MopB_CT_Acetylene-hydratase.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR PANTHER; PTHR43742; TRIMETHYLAMINE-N-OXIDE REDUCTASE; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000313|EMBL:AFV10419.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000467}.
FT DOMAIN 4..291
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 400..489
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
SQ SEQUENCE 525 AA; 59266 MW; D350915D1ACBC1F9 CRC64;
MKRGTKLIVV DPRANWLATR AEHHLQLRPG TDGALALALL YAVIKTDKYD KQFVEKWCYG
FDKLAERVAQ YPPEWAEEIT GVPAEDIYAA AECLVQKPSS ACTGVAIDQN PNCIQIAHAL
YSIFAITGNL DIPGGLFMGQ PQFFAGAAVD SNEDEEEFEG IGYREFPAIP MIVNTTHPDC
TLEALETGKP YPIKFAFIQS TNFLASSIVV QPKRWYEAMR KLEFIVASDI FMNPTIMALA
DLVLPVSTSL EHDGIVMNSM ASQPGQFGAL VKIIDDFGET KSDLEIVLDL YHRLYPDSND
PRWKDPESYL THDMVQIPGI GVTFPELKER VIGQYELEYR KYEKGLLRAD GKPGFNTPTG
KIELYSTILA SLNEDPLPYY IEPKFSAVSR PDIAKEYPLI MTTGARRFTY FHSEHRQISK
LREIHPWPTA EINPKTAAEK GITEGSWIYI ENPWGKAKVV AHVTPIVKEN VVSVDHGWWY
PERDPEKLFD VWEPSINSLI PHKEIGKLGF GTHYKCMPCK IYRAE
//
