ID K4R154_STRDJ Unreviewed; 337 AA.
AC K4R154;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=1-deoxy-D-xylulose-5-phosphate synthase {ECO:0000313|EMBL:CCK26852.1};
DE EC=2.2.1.7 {ECO:0000313|EMBL:CCK26852.1};
GN Name=korB {ECO:0000313|EMBL:CCK26852.1};
GN ORFNames=BN159_2473 {ECO:0000313|EMBL:CCK26852.1};
OS Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1214101 {ECO:0000313|EMBL:CCK26852.1, ECO:0000313|Proteomes:UP000008043};
RN [1] {ECO:0000313|EMBL:CCK26852.1, ECO:0000313|Proteomes:UP000008043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 101723 / JCM 4913 / KCC S-0913 / 768
RC {ECO:0000313|Proteomes:UP000008043};
RX PubMed=23043000; DOI=10.1128/JB.01592-12;
RA Jankowitsch F., Schwarz J., Ruckert C., Gust B., Szczepanowski R., Blom J.,
RA Pelzer S., Kalinowski J., Mack M.;
RT "Genome sequence of the bacterium Streptomyces davawensis JCM 4913 and
RT heterologous production of the unique antibiotic roseoflavin.";
RL J. Bacteriol. 194:6818-6827(2012).
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DR EMBL; HE971709; CCK26852.1; -; Genomic_DNA.
DR RefSeq; WP_015657246.1; NC_020504.1.
DR AlphaFoldDB; K4R154; -.
DR STRING; 1214101.BN159_2473; -.
DR KEGG; sdv:BN159_2473; -.
DR PATRIC; fig|1214101.3.peg.2511; -.
DR eggNOG; COG1013; Bacteria.
DR HOGENOM; CLU_048564_1_0_11; -.
DR OrthoDB; 9775140at2; -.
DR Proteomes; UP000008043; Chromosome.
DR GO; GO:0008661; F:1-deoxy-D-xylulose-5-phosphate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProt.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR CDD; cd03375; TPP_OGFOR; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR Pfam; PF02775; TPP_enzyme_C; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008043};
KW Transferase {ECO:0000313|EMBL:CCK26852.1}.
FT DOMAIN 51..198
FT /note="Thiamine pyrophosphate enzyme TPP-binding"
FT /evidence="ECO:0000259|Pfam:PF02775"
SQ SEQUENCE 337 AA; 36667 MW; EDFE4BBAB3EEF2DE CRC64;
MRLELSARDF KSDQEVRWCP GCGDYAILSA VQGFMPEVGV ARENIVFISG IGCSSRFPYY
MNTYGMHSIH GRAPAIATGL AVSRPDLSVW VVTGDGDALS IGGNHLIHAL RRNVNLKILL
FNNRIYGLTK GQYSPTSELG KITKSTPMGS LDAPFNPVSL AIGAEASFVA RTVDSDRKHL
TEVLRAAHRH PGTALVEIYQ NCNIFNDGAF EVLKDKQQAQ ESVIRLEHGR PILFGTDGAK
GVVRDPATGD LQVVDVTQDN EHRVLIHDAH ADSPTTAFAL SRLADPQTLH HTPIGVFRDI
ERPVYDTTMA DQLEAAVQQN GKGDLAAVLA GSDTWSR
//
