ID K4RFG5_STRDJ Unreviewed; 324 AA.
AC K4RFG5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase 3 {ECO:0000313|EMBL:CCK32335.1};
DE EC=2.3.1.180 {ECO:0000313|EMBL:CCK32335.1};
GN Name=fabH5 {ECO:0000313|EMBL:CCK32335.1};
GN ORFNames=BN159_7956 {ECO:0000313|EMBL:CCK32335.1};
OS Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768).
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1214101 {ECO:0000313|EMBL:CCK32335.1, ECO:0000313|Proteomes:UP000008043};
RN [1] {ECO:0000313|EMBL:CCK32335.1, ECO:0000313|Proteomes:UP000008043}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 101723 / JCM 4913 / KCC S-0913 / 768
RC {ECO:0000313|Proteomes:UP000008043};
RX PubMed=23043000; DOI=10.1128/JB.01592-12;
RA Jankowitsch F., Schwarz J., Ruckert C., Gust B., Szczepanowski R., Blom J.,
RA Pelzer S., Kalinowski J., Mack M.;
RT "Genome sequence of the bacterium Streptomyces davawensis JCM 4913 and
RT heterologous production of the unique antibiotic roseoflavin.";
RL J. Bacteriol. 194:6818-6827(2012).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. FabH family.
CC {ECO:0000256|ARBA:ARBA00008642}.
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DR EMBL; HE971709; CCK32335.1; -; Genomic_DNA.
DR RefSeq; WP_015662661.1; NC_020504.1.
DR AlphaFoldDB; K4RFG5; -.
DR STRING; 1214101.BN159_7956; -.
DR KEGG; sdv:BN159_7956; -.
DR PATRIC; fig|1214101.3.peg.8052; -.
DR eggNOG; COG0332; Bacteria.
DR HOGENOM; CLU_039592_2_0_11; -.
DR OrthoDB; 9815506at2; -.
DR Proteomes; UP000008043; Chromosome.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0033818; F:beta-ketoacyl-acyl-carrier-protein synthase III activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00830; KAS_III; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR InterPro; IPR013747; ACP_syn_III_C.
DR InterPro; IPR013751; ACP_syn_III_N.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR34069; 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE 3; 1.
DR PANTHER; PTHR34069:SF2; BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE III; 1.
DR Pfam; PF08545; ACP_syn_III; 1.
DR Pfam; PF08541; ACP_syn_III_C; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:CCK32335.1};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000008043};
KW Transferase {ECO:0000313|EMBL:CCK32335.1}.
FT DOMAIN 107..178
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08545"
FT DOMAIN 235..324
FT /note="Beta-ketoacyl-[acyl-carrier-protein] synthase III C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF08541"
SQ SEQUENCE 324 AA; 33510 MW; F6476D7BB24CACC0 CRC64;
MTEVGVLGTG AHVPDRVVSN DEAGAGAGVD DAWVVRKTAI RQRRWAAPGQ ATSDLAAAAG
RAALADAGIT ADQVSVIVVA TSTPDRPQPP TAAYVQHLLG AVDASAFDVN AVCSGEVFAL
AAAEGILTRR GGCALVIGAD VYSRILNPAD RRTVVLFGDG AGAMVLGLER GARVRNLATH
TFGELSGLIE VPAGGSRLPA DRAAREAGLH YFTMDGRAVR RFVEDRLPLL TKQFLHESGV
GPDDIAHFVP HQANGVLLDS VFAELALPRA TMHRTLTHYG NTGAAAIPIT VAEAARTGAF
RPGDLILLAG FGGGMAAGFA LVEW
//
