ID K5BEY4_MYCHD Unreviewed; 765 AA.
AC K5BEY4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE SubName: Full=5-methylcytosine-specific restriction enzyme B {ECO:0000313|EMBL:VCT91017.1};
DE EC=3.1.21.- {ECO:0000313|EMBL:VCT91017.1};
DE SubName: Full=AAA domain family protein {ECO:0000313|EMBL:EKF23402.1};
GN Name=mcrB {ECO:0000313|EMBL:VCT91017.1};
GN ORFNames=C731_2596 {ECO:0000313|EMBL:EKF23402.1}, MHAS_02731
GN {ECO:0000313|EMBL:VCT91017.1};
OS Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 /
OS 3849) (Mycobacterium hassiacum).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1122247 {ECO:0000313|EMBL:EKF23402.1, ECO:0000313|Proteomes:UP000006265};
RN [1] {ECO:0000313|EMBL:EKF23402.1, ECO:0000313|Proteomes:UP000006265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 {ECO:0000313|EMBL:EKF23402.1}, and DSM 44199 / CIP
RC 105218 / JCM 12690 / 3849 {ECO:0000313|Proteomes:UP000006265};
RX PubMed=23209251; DOI=10.1128/JB.01880-12;
RA Tiago I., Maranha A., Mendes V., Alarico S., Moynihan P.J., Clarke A.J.,
RA Macedo-Ribeiro S., Pereira P.J., Empadinhas N.;
RT "Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of
RT heat-stable mycobacterial proteins.";
RL J. Bacteriol. 194:7010-7011(2012).
RN [2] {ECO:0000313|EMBL:VCT91017.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mhassiacum {ECO:0000313|EMBL:VCT91017.1};
RA Peiro R., Begona, Cbmso G., Lopez M., Gonzalez S., Sacristan E.,
RA Castillo E.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000268660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 / CIP 105218 / JCM 12690 / 3849
RC {ECO:0000313|Proteomes:UP000268660};
RX PubMed=30701245; DOI=10.1128/mra.01522-18;
RA Sanchez M., Blesa A., Sacristan-Horcajada E., Berenguer J.;
RT "Complete genome sequence of Mycolicibacterium hassiacum DSM 44199.";
RL Microbiol. Resour. Announc. 8:e01522-e01522(2019).
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DR EMBL; AMRA01000069; EKF23402.1; -; Genomic_DNA.
DR EMBL; LR026975; VCT91017.1; -; Genomic_DNA.
DR RefSeq; WP_005628143.1; NZ_LR026975.1.
DR AlphaFoldDB; K5BEY4; -.
DR STRING; 1122247.GCA_000379865_04041; -.
DR REBASE; 57365; Mha44199McrBCP.
DR KEGG; mhas:MHAS_02731; -.
DR PATRIC; fig|1122247.3.peg.2495; -.
DR eggNOG; COG1222; Bacteria.
DR eggNOG; COG1401; Bacteria.
DR Proteomes; UP000006265; Unassembled WGS sequence.
DR Proteomes; UP000268660; Chromosome 1.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd00009; AAA; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR37291; 5-METHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME B; 1.
DR PANTHER; PTHR37291:SF1; TYPE IV METHYL-DIRECTED RESTRICTION ENZYME ECOKMCRB SUBUNIT; 1.
DR Pfam; PF07728; AAA_5; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:VCT91017.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006265}.
FT DOMAIN 478..639
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 765 AA; 84841 MW; 8487985EC266D2F6 CRC64;
MNSGGEAELT EVEVGTFARK ASVAVEAVGR RLIEVGFVGD GSLLTPDRPV WTLANLDVLE
RDYVDKPDTG GDGFFDKLKR QLAGASPTVV QLFAELLILN VLPIINVGGP LKVKQVRSVL
EMSSEPVDLP GDVEAALLGG GVFHGGQAFT TYRWAQLAYL IQVARHFKSL PEQRRSDALA
DPLVFREEVG AVPSGQVAQR HSLLYLAFPH FFLPIVKLEH RTALRDGLAA EYLSEPSGDL
DVDLARIYGA ITEAEGGHVD LYAEPWISRW QKPASSTEPT DQVQHAWKVH GSNVKGQDMV
PIWRTKQSVS LAASLLRPID PYVTRDELKA FVDEDYRSSG YAARQEKFDE FYTFLKRMHP
GDLVVTISQG MVYFGTVTGP AEFTPSSDGR SNLRRSVKWF EHPCPWSDVP SDIAARLSAQ
GEVLDLSQHL EQLLALAERR PQPPSPVEVH LPDATQELAD RIHVGTDWLQ DCVELLRERR
QIIFYGPPGT GKTYIAQQLA WHVTDKANVK LVQFHPAYSY EDFFEGFRPQ GEAGGHIGFT
LKAGPLRSLV DKAAENPEAA YVLIIDEINR GNLPKIFGEL YFLLEYRDQA IDLMYSSDSA
EPFSLPKNIF VIGTMNTADR SIALVDAALR RRFAFLPLHP SEEPTSGILR SWLAANGYDT
TLADLHEELN ARISDSDFKI GPSYFMRKKI ATDPTGKALE LMWRTDILPL LEEHHFGDRN
VDVPGRYGLP ALWKALAAKS AAAVDDEELP VLDTGDDDAD TADPH
//
