ID K5BIY0_MYCHD Unreviewed; 322 AA.
AC K5BIY0;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Bacterial regulatory helix-turn-helix, lysR family protein {ECO:0000313|EMBL:EKF22149.1};
GN ORFNames=C731_3896 {ECO:0000313|EMBL:EKF22149.1};
OS Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 /
OS 3849) (Mycobacterium hassiacum).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1122247 {ECO:0000313|EMBL:EKF22149.1, ECO:0000313|Proteomes:UP000006265};
RN [1] {ECO:0000313|EMBL:EKF22149.1, ECO:0000313|Proteomes:UP000006265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 / CIP 105218 / JCM 12690 / 3849
RC {ECO:0000313|Proteomes:UP000006265};
RX PubMed=23209251; DOI=10.1128/JB.01880-12;
RA Tiago I., Maranha A., Mendes V., Alarico S., Moynihan P.J., Clarke A.J.,
RA Macedo-Ribeiro S., Pereira P.J., Empadinhas N.;
RT "Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of
RT heat-stable mycobacterial proteins.";
RL J. Bacteriol. 194:7010-7011(2012).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00009437}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF22149.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMRA01000104; EKF22149.1; -; Genomic_DNA.
DR RefSeq; WP_005630603.1; NZ_LR026975.1.
DR AlphaFoldDB; K5BIY0; -.
DR STRING; 1122247.GCA_000379865_02421; -.
DR PATRIC; fig|1122247.3.peg.3737; -.
DR eggNOG; COG0583; Bacteria.
DR OrthoDB; 570111at2; -.
DR Proteomes; UP000006265; Unassembled WGS sequence.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR Gene3D; 3.40.190.290; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30537; HTH-TYPE TRANSCRIPTIONAL REGULATOR; 1.
DR PANTHER; PTHR30537:SF3; RUBISCO TRANSCRIPTIONAL REGULATOR-RELATED; 1.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006265}.
FT DOMAIN 23..80
FT /note="HTH lysR-type"
FT /evidence="ECO:0000259|PROSITE:PS50931"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 322 AA; 34598 MW; 7A58F27C63949304 CRC64;
MSGAETGHHL PTRDSARPAG RRPSADDLLV LLAVGRSGRF TTAAAELGLN HTTISRRIAA
LEQALGGRVL TRVAGGWELT DLGREALAAA ESIEGALRAL TARADGERAL EGVVRMSATD
GFSAYIAAPA AARVQRRHPG VAVEIVTATR RASQQRSGLD VEVVVGEPKV HRAEAIRLGD
YCLGLYGARD YLAAHGTPTE IADLDRFPLV YFIDSMLQVD DLDLATNFAP AMRQSVSSTN
VFVHVEATRA AAGLGLLPCF MADRHPDLIR VLPDAVAVRL TYWLVARSET LRRPEVAAVV
DAIRDRMTEL REVLLGKRCL PG
//
