ID K5BJN3_MYCHD Unreviewed; 2412 AA.
AC K5BJN3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=AAA domain protein {ECO:0000313|EMBL:EKF23414.1};
DE SubName: Full=RecBCD enzyme subunit RecD {ECO:0000313|EMBL:VCT88389.1};
DE EC=3.1.11.5 {ECO:0000313|EMBL:VCT88389.1};
GN Name=recD_1 {ECO:0000313|EMBL:VCT88389.1};
GN ORFNames=C731_2568 {ECO:0000313|EMBL:EKF23414.1}, MHAS_00069
GN {ECO:0000313|EMBL:VCT88389.1};
OS Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 /
OS 3849) (Mycobacterium hassiacum).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1122247 {ECO:0000313|EMBL:EKF23414.1, ECO:0000313|Proteomes:UP000006265};
RN [1] {ECO:0000313|EMBL:EKF23414.1, ECO:0000313|Proteomes:UP000006265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 {ECO:0000313|EMBL:EKF23414.1}, and DSM 44199 / CIP
RC 105218 / JCM 12690 / 3849 {ECO:0000313|Proteomes:UP000006265};
RX PubMed=23209251; DOI=10.1128/JB.01880-12;
RA Tiago I., Maranha A., Mendes V., Alarico S., Moynihan P.J., Clarke A.J.,
RA Macedo-Ribeiro S., Pereira P.J., Empadinhas N.;
RT "Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of
RT heat-stable mycobacterial proteins.";
RL J. Bacteriol. 194:7010-7011(2012).
RN [2] {ECO:0000313|EMBL:VCT88389.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mhassiacum {ECO:0000313|EMBL:VCT88389.1};
RA Peiro R., Begona, Cbmso G., Lopez M., Gonzalez S., Sacristan E.,
RA Castillo E.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000268660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 / CIP 105218 / JCM 12690 / 3849
RC {ECO:0000313|Proteomes:UP000268660};
RX PubMed=30701245; DOI=10.1128/mra.01522-18;
RA Sanchez M., Blesa A., Sacristan-Horcajada E., Berenguer J.;
RT "Complete genome sequence of Mycolicibacterium hassiacum DSM 44199.";
RL Microbiol. Resour. Announc. 8:e01522-e01522(2019).
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DR EMBL; AMRA01000067; EKF23414.1; -; Genomic_DNA.
DR EMBL; LR026975; VCT88389.1; -; Genomic_DNA.
DR RefSeq; WP_005628075.1; NZ_LR026975.1.
DR STRING; 1122247.GCA_000379865_03758; -.
DR KEGG; mhas:MHAS_00069; -.
DR PATRIC; fig|1122247.3.peg.2469; -.
DR eggNOG; COG0507; Bacteria.
DR eggNOG; COG1112; Bacteria.
DR OrthoDB; 9757917at2; -.
DR Proteomes; UP000006265; Unassembled WGS sequence.
DR Proteomes; UP000268660; Chromosome 1.
DR GO; GO:0008854; F:exodeoxyribonuclease V activity; IEA:UniProtKB-EC.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.10.620.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR025103; DUF4011.
DR InterPro; IPR041650; HEPN_Swt1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049468; Restrct_endonuc-II-like_dom.
DR InterPro; IPR047187; SF1_C_Upf1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF525; HELICASE SENATAXIN-RELATED; 1.
DR Pfam; PF13086; AAA_11; 2.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF13195; DUF4011; 1.
DR Pfam; PF18731; HEPN_Swt1; 1.
DR Pfam; PF18741; MTES_1575; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:VCT88389.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006265}.
FT DOMAIN 13..128
FT /note="Swt1-like HEPN"
FT /evidence="ECO:0000259|Pfam:PF18731"
FT DOMAIN 853..956
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1465..1528
FT /note="DNA2/NAM7 helicase helicase"
FT /evidence="ECO:0000259|Pfam:PF13086"
FT DOMAIN 1550..1749
FT /note="DNA2/NAM7 helicase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13087"
FT DOMAIN 1800..1896
FT /note="Restriction endonuclease type II-like"
FT /evidence="ECO:0000259|Pfam:PF18741"
FT REGION 148..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1904..1951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2412 AA; 265549 MW; 6C1E90E2765C8374 CRC64;
MPDRDYHPVV GEAIHIVIGG LQPFVERVMA RALPPGVEWT EVIRLKDVAN NRRGGEYRPN
DLSLMLRAMT ERLGDYGYPF SNHMSRQAQT YASELRDIRN RWAHTEFFSA PDAYRAIDTI
ELLLRAIGAE PEAAQVAQLK PRVVPIAGPG AGSGKPTGAQ PAGAPNGCGS ASAPSAATSP
KPPKPSAPQP SQAGAPRIEI EAVTELSYPM AHCGIPVIEH ITVEPAGNDI RSAVLEVDVV
SAHGSHGGPQ QIFLDVAANR PTIVRDVDLK LDPAAMLQVS DQCPGSLRAV LRNAAGEVLA
EASKDVNILA ANQWKATPLQ LALEMLATHV QPNSIAVNAL MVEVSDRLQS LTGNSAIDGY
QSENPERVDA IAQAVFEAMQ GRDIRYSEPP ASWGDDGQKI RTPAEVLEGR LGTCLDTTLT
MAAVLEQAGI NATIWVLNGH AFLGYWRRDA ALGSVSTTEV VDVVNQVELG NIRLVETTMV
TQPDAAFADA TNAPRTRYLT GDLTEILGVT DIRQARFGRI YPLPSREKDA DGNTVVTQYT
PPEAPAIEVS VTGAGGQRSG DGEPVPARIR QWKNALLDLS LRNKLINYTE RSGYRVEVPG
PALGRFEDIV NAGVTINLLA SDAVKSVDRA RGIRYGRDLP ENDRELLLAD KHSVYIDITD
ASYQSKLRYL AYKAKTIVEE TGSNNLYLAF GMLNWRFNDR DLRSPLILVP VTLTTTNRGQ
RYVLTIDEAG ASTPNYCLVE KLRVSFGLEI PGLANPTEDD SGIDLELSFN AVREAVAKAG
LSFRVEETVH LSILQFAKFP LWKDLDESWA ELSRNSLVTH LINSPNEKFS DPVNEPPQVD
LDELGASLPM PADSSQLQAV AEAVAGRTFV LEGPPGTGKS QTITNLLAHA MVSGRRVLFV
AEKRAALDVV KDRLERVGLG ELSLDLHDKS ARPAAVRQQI KQALELRVNH DAAALKTNLQ
TVESSRRVLA RYADRLHETN AAGLSLYTAR SSELAADQEI APLTVPPTLV ASGDPETFEN
LSRLFRDLPE KADLARPSQR HPWGFIDVAD PGALNPSEIH AAAVEFDQAL IDLLDRGVDL
DQIARAGDSY EVFIWADLTT APRYPIEGLD ELHSESWKAE LAAIKQRANQ IAASKPSWSA
TVTPAAMDLD IPAIHQAAVD ADNSGFFGRR KRRRAVLERL SSVLCVEAKT VKLKTLSTLT
GEILETFEAV QQLRERVAKI PVAIMPDPWN PLVDEDTKKL IENLDLIDWL VATLCSEREY
PYVDVLRDYY ASRPSGELAE PVERLAKSWA RLTKVTGVER TQQQAWADPD PFLARWWETR
AARRLETTAT IDRWVDLLRH VQPLRAVGMD EARADILSGK IVAEDAALAF DRGIAAASVS
ERFEASALND FDVEAHSKAI KRFATGTSAV REELCRAIPA KLLGQRSFDP DAGGRIGNLR
RQLDRKRGGM SVRALMENYG DLITQILPCT LMSPESVARF FPAKAELFDI VVFDEASQIR
VADAIGAMGR AKSVVVVGDS KQMPPTSFAE VSATIDEEAE FDESIVPDEE SILTECVKAF
VPQQWLSWHY RSQDEALIAF SNYHYYENRL ASFPAPLPAS GSGARGHGIS LVRVDGHFER
KARGKSLRTN RVEAERIVED VKQRFAQSPD KAPSLGVITF NAQQRDLIEN LLRDTGDDRI
LQALDQPDGL FVKNLENVQG DERDTILFSV AFSADDKGVV PLNFGPLSKP GGERRLNVAI
TRARREVVLY ASFDPSELRA EETTQLGTKH LKAYLELAAR GVQTVTDGGK RQPVFDRHRD
DIAEALRDTG LIVQTDVGLS DFRVDLVISS PDQPEQPLVA VLLDGPDWYG RRTVSDRDAL
PVEVLDRLMK WPGVERVWLP EWLHRREATI ERLKKAVEEA QEKLARRAEE ASDVSSAPAT
ESPRPEPVPV SGRSAAAVEP SRGEAEAPRQ FATLRSAPTA TVERGETQHP LIKPYQEYRL
LTPDWGDYGI AVEPDFVPAI RSLYPDEWSD DARHLRTDAQ LVPEPAGSRG RWAISVRAHG
KTIGYLGADQ EETWSGVIRR VIASGYIPTT SCQIYAYGDF YWDDKDYLPD VRIALGDPAV
ALPINNPPEV PYTLLPKSSS FQVTRTEEYF DILSQYVPEG GYGVLFVTLH AGQPAGSGKP
YVEVRIDGKR VGRLTPQTSQ RLLPLIRHFE ARGFVTVCRG NIKGSALAVE LRITAIKAHE
ATPEVLDGPP ITVPSLVPRR EDPLQYDLSK LAPVLEPLPL VPPPPMLAEP GDGTVIRFYK
GGGRYVYVAI RRGRYWETTS TGAWRSMKPR MNWETLGSQL PSAEVVTAWS DVKTQVDARV
RQYGAVVQFT VGRHRIAAVN IDDSGDDEGD WYTTVSDDLE SELRLGKFAR WSEIVRYGSQ
VQVAVRWRSL RD
//
