ID K5BKQ4_MYCHD Unreviewed; 163 AA.
AC K5BKQ4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Beta-carbonic anhydrase 1 {ECO:0000313|EMBL:VCT93094.1};
DE EC=4.2.1.1 {ECO:0000313|EMBL:VCT93094.1};
DE SubName: Full=Carbonic anhydrase family protein {ECO:0000313|EMBL:EKF25269.1};
GN Name=mtcA1 {ECO:0000313|EMBL:VCT93094.1};
GN ORFNames=C731_0701 {ECO:0000313|EMBL:EKF25269.1}, MHAS_04832
GN {ECO:0000313|EMBL:VCT93094.1};
OS Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 /
OS 3849) (Mycobacterium hassiacum).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycolicibacterium.
OX NCBI_TaxID=1122247 {ECO:0000313|EMBL:EKF25269.1, ECO:0000313|Proteomes:UP000006265};
RN [1] {ECO:0000313|EMBL:EKF25269.1, ECO:0000313|Proteomes:UP000006265}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 {ECO:0000313|EMBL:EKF25269.1}, and DSM 44199 / CIP
RC 105218 / JCM 12690 / 3849 {ECO:0000313|Proteomes:UP000006265};
RX PubMed=23209251; DOI=10.1128/JB.01880-12;
RA Tiago I., Maranha A., Mendes V., Alarico S., Moynihan P.J., Clarke A.J.,
RA Macedo-Ribeiro S., Pereira P.J., Empadinhas N.;
RT "Genome sequence of Mycobacterium hassiacum DSM 44199, a rare source of
RT heat-stable mycobacterial proteins.";
RL J. Bacteriol. 194:7010-7011(2012).
RN [2] {ECO:0000313|EMBL:VCT93094.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mhassiacum {ECO:0000313|EMBL:VCT93094.1};
RA Peiro R., Begona, Cbmso G., Lopez M., Gonzalez S., Sacristan E.,
RA Castillo E.;
RL Submitted (OCT-2018) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Proteomes:UP000268660}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 44199 / CIP 105218 / JCM 12690 / 3849
RC {ECO:0000313|Proteomes:UP000268660};
RX PubMed=30701245; DOI=10.1128/mra.01522-18;
RA Sanchez M., Blesa A., Sacristan-Horcajada E., Berenguer J.;
RT "Complete genome sequence of Mycolicibacterium hassiacum DSM 44199.";
RL Microbiol. Resour. Announc. 8:e01522-e01522(2019).
CC -!- FUNCTION: Catalyzes the reversible hydration of carbon dioxide to form
CC bicarbonate. {ECO:0000256|ARBA:ARBA00024993}.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the beta-class carbonic anhydrase family.
CC {ECO:0000256|ARBA:ARBA00006217}.
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DR EMBL; AMRA01000019; EKF25269.1; -; Genomic_DNA.
DR EMBL; LR026975; VCT93094.1; -; Genomic_DNA.
DR RefSeq; WP_005624665.1; NZ_LR026975.1.
DR AlphaFoldDB; K5BKQ4; -.
DR STRING; 1122247.GCA_000379865_03536; -.
DR KEGG; mhas:MHAS_04832; -.
DR PATRIC; fig|1122247.3.peg.673; -.
DR eggNOG; COG0288; Bacteria.
DR OrthoDB; 8968066at2; -.
DR Proteomes; UP000006265; Unassembled WGS sequence.
DR Proteomes; UP000268660; Chromosome 1.
DR GO; GO:0004089; F:carbonate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd03379; beta_CA_cladeD; 1.
DR Gene3D; 3.40.1050.10; Carbonic anhydrase; 1.
DR InterPro; IPR001765; Carbonic_anhydrase.
DR InterPro; IPR036874; Carbonic_anhydrase_sf.
DR PANTHER; PTHR43175:SF3; CARBON DISULFIDE HYDROLASE; 1.
DR PANTHER; PTHR43175; CARBONIC ANHYDRASE; 1.
DR Pfam; PF00484; Pro_CA; 1.
DR SMART; SM00947; Pro_CA; 1.
DR SUPFAM; SSF53056; beta-carbonic anhydrase, cab; 1.
PE 3: Inferred from homology;
KW Lyase {ECO:0000313|EMBL:VCT93094.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000006265}.
SQ SEQUENCE 163 AA; 18357 MW; BAF6F16C55F2AAA9 CRC64;
MSVTDEYLKN NEEYAKTFKG PLPLPPSKHV AVVACMDARL DVYRILGLKD GEAHVIRNAG
GVITDDEIRS LAISQRLLGT REIMLIHHTD CGMLTFTDDE FKRQIQEETG IKPEWAAESF
TDLEEDVRQS LRRIEASPFV TLHTSARGFI FDVATGKLHE VTL
//
