ID K5V286_PHACS Unreviewed; 424 AA.
AC K5V286;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Carnosine N-methyltransferase {ECO:0000256|ARBA:ARBA00015448};
DE EC=2.1.1.22 {ECO:0000256|ARBA:ARBA00012003};
GN ORFNames=PHACADRAFT_194233 {ECO:0000313|EMBL:EKM56641.1};
OS Phanerochaete carnosa (strain HHB-10118-sp) (White-rot fungus) (Peniophora
OS carnosa).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Phanerochaetaceae; Phanerochaete.
OX NCBI_TaxID=650164 {ECO:0000313|EMBL:EKM56641.1, ECO:0000313|Proteomes:UP000008370};
RN [1] {ECO:0000313|EMBL:EKM56641.1, ECO:0000313|Proteomes:UP000008370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB-10118-sp {ECO:0000313|EMBL:EKM56641.1,
RC ECO:0000313|Proteomes:UP000008370};
RX PubMed=22937793; DOI=10.1186/1471-2164-13-444;
RA Suzuki H., MacDonald J., Syed K., Salamov A., Hori C., Aerts A.,
RA Henrissat B., Wiebenga A., vanKuyk P.A., Barry K., Lindquist E.,
RA LaButti K., Lapidus A., Lucas S., Coutinho P., Gong Y., Samejima M.,
RA Mahadevan R., Abou-Zaid M., de Vries R.P., Igarashi K., Yadav J.S.,
RA Grigoriev I.V., Master E.R.;
RT "Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P.
RT chrysosporium, to elucidate the genetic basis of the distinct wood types
RT they colonize.";
RL BMC Genomics 13:444-444(2012).
CC -!- SIMILARITY: Belongs to the carnosine N-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010086}.
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DR EMBL; JH930471; EKM56641.1; -; Genomic_DNA.
DR RefSeq; XP_007394483.1; XM_007394421.1.
DR AlphaFoldDB; K5V286; -.
DR STRING; 650164.K5V286; -.
DR GeneID; 18910980; -.
DR KEGG; pco:PHACADRAFT_194233; -.
DR HOGENOM; CLU_030612_1_1_1; -.
DR InParanoid; K5V286; -.
DR OrthoDB; 167229at2759; -.
DR Proteomes; UP000008370; Unassembled WGS sequence.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR012901; CARME.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12303:SF6; CARNOSINE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12303; UNCHARACTERIZED; 1.
DR Pfam; PF07942; CARME; 1.
DR SMART; SM01296; N2227; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000008370};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 86..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 424 AA; 48060 MW; 6D4CC167C66FC8DA CRC64;
MPRSFEQEDI EEEQRHLANV IATFNQYASY SLSANNRRRK DIYKLPRGDQ ELLTVLGYKT
KLHEVDEAII ANDKFLKQII ADPEIFGHDV DPENEKNEEQ DYHEQEGIQD SQASHSHAHD
DPSHSHSHGH GGHSHSHAAS GGHAGHSPSG GKYRPTENDV DKLRSTIKQF VRDWSEEGKG
ERNLCYEPMK QALVEHFAHV PAEERSRLRV LVPGAGLCRL AWDVANLGFA CQGNEFSHYM
LLASFFILNR TTKVNEHTIY PYIHSFSNLT DKNALLRPIS FPDVSPSSLP SNSNFSLVAG
DFEEVYGPDD YEYGEPQAGL WDAILTCFFI DTAKNIVNYL RIIHRKLAPG GVWINMGPLL
WHWENNSSGD TSIELNVEEL KELARKIGFE ICDERTIDTT YTNNSQSMLG YIYHTAFFTA
TKKA
//
