ID K5VK26_PHACS Unreviewed; 1305 AA.
AC K5VK26;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 46.
DE RecName: Full=Condensin complex subunit 1 {ECO:0000256|PIRNR:PIRNR017127};
GN ORFNames=PHACADRAFT_150370 {ECO:0000313|EMBL:EKM51723.1};
OS Phanerochaete carnosa (strain HHB-10118-sp) (White-rot fungus) (Peniophora
OS carnosa).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Phanerochaetaceae; Phanerochaete.
OX NCBI_TaxID=650164 {ECO:0000313|EMBL:EKM51723.1, ECO:0000313|Proteomes:UP000008370};
RN [1] {ECO:0000313|EMBL:EKM51723.1, ECO:0000313|Proteomes:UP000008370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB-10118-sp {ECO:0000313|EMBL:EKM51723.1,
RC ECO:0000313|Proteomes:UP000008370};
RX PubMed=22937793; DOI=10.1186/1471-2164-13-444;
RA Suzuki H., MacDonald J., Syed K., Salamov A., Hori C., Aerts A.,
RA Henrissat B., Wiebenga A., vanKuyk P.A., Barry K., Lindquist E.,
RA LaButti K., Lapidus A., Lucas S., Coutinho P., Gong Y., Samejima M.,
RA Mahadevan R., Abou-Zaid M., de Vries R.P., Igarashi K., Yadav J.S.,
RA Grigoriev I.V., Master E.R.;
RT "Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P.
RT chrysosporium, to elucidate the genetic basis of the distinct wood types
RT they colonize.";
RL BMC Genomics 13:444-444(2012).
CC -!- FUNCTION: Regulatory subunit of the condensin complex, a complex
CC required for conversion of interphase chromatin into mitotic-like
CC condense chromosomes. The condensin complex probably introduces
CC positive supercoils into relaxed DNA in the presence of type I
CC topoisomerases and converts nicked DNA into positive knotted forms in
CC the presence of type II topoisomerases.
CC {ECO:0000256|PIRNR:PIRNR017127}.
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CND1 (condensin subunit 1) family.
CC {ECO:0000256|ARBA:ARBA00009606, ECO:0000256|PIRNR:PIRNR017127}.
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DR EMBL; JH930476; EKM51723.1; -; Genomic_DNA.
DR RefSeq; XP_007399528.1; XM_007399466.1.
DR STRING; 650164.K5VK26; -.
DR GeneID; 18908839; -.
DR KEGG; pco:PHACADRAFT_150370; -.
DR HOGENOM; CLU_001867_2_1_1; -.
DR InParanoid; K5VK26; -.
DR OrthoDB; 5480287at2759; -.
DR Proteomes; UP000008370; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007076; P:mitotic chromosome condensation; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026971; CND1/NCAPD3.
DR InterPro; IPR032682; Cnd1_C.
DR InterPro; IPR007673; Condensin_cplx_su1.
DR InterPro; IPR024324; Condensin_cplx_su1_N.
DR PANTHER; PTHR14222; CONDENSIN; 1.
DR PANTHER; PTHR14222:SF2; CONDENSIN COMPLEX SUBUNIT 1; 1.
DR Pfam; PF12717; Cnd1; 1.
DR Pfam; PF12922; Cnd1_N; 1.
DR PIRSF; PIRSF017127; Condensin_D2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|PIRNR:PIRNR017127};
KW Cell division {ECO:0000256|ARBA:ARBA00022618,
KW ECO:0000256|PIRNR:PIRNR017127}; Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW DNA condensation {ECO:0000256|ARBA:ARBA00023067,
KW ECO:0000256|PIRNR:PIRNR017127};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776, ECO:0000256|PIRNR:PIRNR017127};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008370}.
FT DOMAIN 43..213
FT /note="Condensin complex subunit 1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF12922"
FT DOMAIN 1039..1199
FT /note="Condensin complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12717"
FT REGION 101..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..516
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 839..880
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 922..943
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1264..1305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..472
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..491
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 500..516
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1264..1280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1305 AA; 147519 MW; 238A70B932F36E8E CRC64;
MVSALLEGAV VAIADSSDNI TQPQVFDAYR SLLKYAEHLQ GTTMSKLLDS ISSAFQSQVD
ATIRDIEAEE QDTYILHKTA LEMYAFLLQW FVTAAEKVKV TGDEDAPAQP PRARRGRGGK
AAAARAVAAR RTEHWSWQDQ IPAALMLVSK VLRLRTQRLW TTTPEKDTFI NCLLVPAYRI
SENEGYMKSQ EIRLGVYKCV CLAVKHHGHI LTAQITIMQS LQYYEHLSEP MAECLMILSK
EFDHSQLCDE ILREIAGKAF NAQDTKGPRA FSRFLVRLTE LAPRLVLKQI SLLLTHLDSE
SYPMRMALVE VIGHLIREIA VSADLNMDQQ QSQKQLNGLY DLLLERTLDL SSYVRTKVLS
TLAKLCDLPV KFPKQRLAIT RAAVDCLEDK AAGVRKTAVL LIVKLIVTHP YGLMHGGLLG
QREWETRYEA VVQELQKVEK EVAKAVQRVD GDARDGDEEG KEGEDEEVMD GADDAEEKPR
KKKRQAHERD DDVEMADEEG GTEAQPKREK KPRKSQLNID ALQSEAEAMA ILDSNEMLHL
KLRKRYYAEG LSFIRQIEQG MKVIEQLLAS TSKAEVLEAM EFFRVAHEYQ FDGAEVGIKK
MLHLIWHKDH SSTNEDGKEL KGIRPRLLEC YRSLYFDPLP DMEPKQQVNR IAKNMIELTY
DATLAELTSL EETMRIMMED SQVHNDVITK LWQVYSSERP LPRAQRRGAV IILGMLALAR
RSVVADRVDT LVKIGLGKLG QTDLLLARYT CVAIQRLNGS AKKVKGSLLD KSIRLELDNP
LFRKLQDALE HPCRHKDWFG MAEQAINTVY ALAERPDVFC DGLIKNLARR VFGVKQGKEV
RSASVGTPDP DAGPDAMVLD EDNAEPNSTP GPASAASAAE AGDKDVGDAF ELSQLLFVVG
HVAIKQIVFL ELVEREWKRQ KHEHERAEKA TRGPQADKNA SKDTVEELDQ VVGNAEDDIG
DRITHIREQE LLFDHNSLLT SFGPMLVHIC GSPHKFKNRI LRAAATLAFS KFLCVSSTFC
DQHHQLLFRI LDTSKDPSIR SNIAIALGDV AVSFSTVIDE NSDELYKGLS DKDIIVKKNT
LMVLTHLILN GMIKVKGQLG EMAKCLEDSD ERIADLAKLF FSELATKDNA IYNNLPDVIS
HLSVGTHAVD EEAFQSTMRY IFKFIEKEKQ AENIVEKLCQ RFRLSEESRQ WRDIAFCLSL
LPFKSERSVK KLVEGLPFYR DKLHEEDVYA RFQEILAKAR SNKSPNKPET ELNEFESILD
EHRRQGAEDQ AFEKRVEKNK AAARKKAGRR SARKKATVQE EQEEE
//
