ID K5VM36_PHACS Unreviewed; 364 AA.
AC K5VM36;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 13-SEP-2023, entry version 39.
DE RecName: Full=MutL C-terminal dimerisation domain-containing protein {ECO:0000259|SMART:SM00853};
DE Flags: Fragment;
GN ORFNames=PHACADRAFT_260955 {ECO:0000313|EMBL:EKM52503.1};
OS Phanerochaete carnosa (strain HHB-10118-sp) (White-rot fungus) (Peniophora
OS carnosa).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Phanerochaetaceae; Phanerochaete.
OX NCBI_TaxID=650164 {ECO:0000313|EMBL:EKM52503.1, ECO:0000313|Proteomes:UP000008370};
RN [1] {ECO:0000313|EMBL:EKM52503.1, ECO:0000313|Proteomes:UP000008370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB-10118-sp {ECO:0000313|EMBL:EKM52503.1,
RC ECO:0000313|Proteomes:UP000008370};
RX PubMed=22937793; DOI=10.1186/1471-2164-13-444;
RA Suzuki H., MacDonald J., Syed K., Salamov A., Hori C., Aerts A.,
RA Henrissat B., Wiebenga A., vanKuyk P.A., Barry K., Lindquist E.,
RA LaButti K., Lapidus A., Lucas S., Coutinho P., Gong Y., Samejima M.,
RA Mahadevan R., Abou-Zaid M., de Vries R.P., Igarashi K., Yadav J.S.,
RA Grigoriev I.V., Master E.R.;
RT "Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P.
RT chrysosporium, to elucidate the genetic basis of the distinct wood types
RT they colonize.";
RL BMC Genomics 13:444-444(2012).
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DR EMBL; JH930475; EKM52503.1; -; Genomic_DNA.
DR RefSeq; XP_007398846.1; XM_007398784.1.
DR AlphaFoldDB; K5VM36; -.
DR STRING; 650164.K5VM36; -.
DR GeneID; 18917855; -.
DR KEGG; pco:PHACADRAFT_260955; -.
DR HOGENOM; CLU_045861_0_0_1; -.
DR InParanoid; K5VM36; -.
DR OrthoDB; 4698638at2759; -.
DR Proteomes; UP000008370; Unassembled WGS sequence.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.1540.20; MutL, C-terminal domain, dimerisation subdomain; 1.
DR Gene3D; 3.30.1370.100; MutL, C-terminal domain, regulatory subdomain; 1.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR014790; MutL_C.
DR InterPro; IPR042120; MutL_C_dimsub.
DR InterPro; IPR042121; MutL_C_regsub.
DR InterPro; IPR037198; MutL_C_sf.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF52; MISMATCH REPAIR ENDONUCLEASE PMS2; 1.
DR Pfam; PF08676; MutL_C; 1.
DR SMART; SM00853; MutL_C; 1.
DR SUPFAM; SSF118116; DNA mismatch repair protein MutL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008370}.
FT DOMAIN 162..324
FT /note="MutL C-terminal dimerisation"
FT /evidence="ECO:0000259|SMART:SM00853"
FT REGION 1..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 343..364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..24
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..46
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 364
FT /evidence="ECO:0000313|EMBL:EKM52503.1"
SQ SEQUENCE 364 AA; 40133 MW; 8912C12D7757B927 CRC64;
MVRGESEEED ANENDQEMDE VAVEEESEMV ARSQGSSQQN DGRSNSPEPG AADATPETST
DRLEPAAPDS NISGSPKQIP IEIVKAAGTE VVDLHFDLSA TSSTWRRLGD SSGIERATKE
LHVPASSLAQ EAGIDVGEDN GTRIEEALSR VITKDDFASM EILGQFNLGF IIVRRYGVHA
GSADSAFPVD DLFIVDQHAA DEKYNFETLQ QTTKINSQAL IRPKLLELTA SDELLALENI
DILRQNGFEI DTEGGSEEQG ESRRRLRLVA QPVSKSTVFD IKDLEELLHL LRDRPRGQMV
RCSKARAMFA SRACRKSVMV GMPLKTQQMT AIVRHMGTMD QPWNCPHGRP TMRHLSDISS
LGRD
//
