ID K5W5Q6_AGABU Unreviewed; 342 AA.
AC K5W5Q6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=VWFA domain-containing protein {ECO:0000259|PROSITE:PS50234};
GN ORFNames=AGABI1DRAFT_112251 {ECO:0000313|EMBL:EKM82134.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM82134.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
CC -!- SIMILARITY: Belongs to the proteasome subunit S5A family.
CC {ECO:0000256|ARBA:ARBA00005574}.
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DR EMBL; JH971387; EKM82134.1; -; Genomic_DNA.
DR RefSeq; XP_007327860.1; XM_007327798.1.
DR AlphaFoldDB; K5W5Q6; -.
DR STRING; 597362.K5W5Q6; -.
DR GeneID; 18823566; -.
DR KEGG; abp:AGABI1DRAFT112251; -.
DR eggNOG; KOG2884; Eukaryota.
DR HOGENOM; CLU_033293_1_0_1; -.
DR InParanoid; K5W5Q6; -.
DR OMA; QMSMQDQ; -.
DR OrthoDB; 169547at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.3990; -; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR InterPro; IPR003903; UIM_dom.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR10223; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; 1.
DR PANTHER; PTHR10223:SF0; 26S PROTEASOME NON-ATPASE REGULATORY SUBUNIT 4; 1.
DR Pfam; PF02809; UIM; 3.
DR Pfam; PF13519; VWA_2; 1.
DR SMART; SM00726; UIM; 3.
DR SMART; SM00327; VWA; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50330; UIM; 3.
DR PROSITE; PS50234; VWFA; 1.
PE 3: Inferred from homology;
KW Proteasome {ECO:0000256|ARBA:ARBA00022942};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493}.
FT DOMAIN 5..197
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 206..230
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..273
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..293
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 294..319
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 328..342
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 37382 MW; 3ACA4185E7379498 CRC64;
MPLEATMMII DNSEYMRNGD YQPTRFHAQS DAVTNVFQTK IDSNPENTVG VMTMAGKGPE
VLVTHTKDIG QILQGLHVAT SKIGGEIDIP TAIAVAQLAL KHRENKNLRQ RIIVFVASPL
DGQAADEKAM VRLAKKLKKN NVAIDVICFG DGIEEAAEDG KTVLRTFVES ANSSDNSHLV
TIPPSTRLLS EQIANSAILA ADRGAGIPDE FMPRDGPAPS SSNGNEYEFG VDPNVDPELA
MALRMSMREA QAREAAEAAT TSQPNPTEST TQPPTGEEDE DEELRKALAM SEEKDVEMED
DEFDDDEDDD EDEEDEEAAI ARAIEMSMQE QKDQDKDSSK QK
//
