ID K5WIJ9_PHACS Unreviewed; 538 AA.
AC K5WIJ9;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 22-FEB-2023, entry version 34.
DE RecName: Full=DNA polymerase epsilon subunit {ECO:0000256|PIRNR:PIRNR000799};
DE AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|PIRNR:PIRNR000799};
GN ORFNames=PHACADRAFT_181204 {ECO:0000313|EMBL:EKM59210.1};
OS Phanerochaete carnosa (strain HHB-10118-sp) (White-rot fungus) (Peniophora
OS carnosa).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Phanerochaetaceae; Phanerochaete.
OX NCBI_TaxID=650164 {ECO:0000313|EMBL:EKM59210.1, ECO:0000313|Proteomes:UP000008370};
RN [1] {ECO:0000313|EMBL:EKM59210.1, ECO:0000313|Proteomes:UP000008370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB-10118-sp {ECO:0000313|EMBL:EKM59210.1,
RC ECO:0000313|Proteomes:UP000008370};
RX PubMed=22937793; DOI=10.1186/1471-2164-13-444;
RA Suzuki H., MacDonald J., Syed K., Salamov A., Hori C., Aerts A.,
RA Henrissat B., Wiebenga A., vanKuyk P.A., Barry K., Lindquist E.,
RA LaButti K., Lapidus A., Lucas S., Coutinho P., Gong Y., Samejima M.,
RA Mahadevan R., Abou-Zaid M., de Vries R.P., Igarashi K., Yadav J.S.,
RA Grigoriev I.V., Master E.R.;
RT "Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P.
RT chrysosporium, to elucidate the genetic basis of the distinct wood types
RT they colonize.";
RL BMC Genomics 13:444-444(2012).
CC -!- FUNCTION: Participates in DNA repair and in chromosomal DNA
CC replication. {ECO:0000256|PIRNR:PIRNR000799}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR000799}.
CC -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC {ECO:0000256|ARBA:ARBA00009560, ECO:0000256|PIRNR:PIRNR000799}.
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DR EMBL; JH930469; EKM59210.1; -; Genomic_DNA.
DR RefSeq; XP_007391780.1; XM_007391718.1.
DR AlphaFoldDB; K5WIJ9; -.
DR STRING; 650164.K5WIJ9; -.
DR GeneID; 18910003; -.
DR KEGG; pco:PHACADRAFT_181204; -.
DR HOGENOM; CLU_010628_2_1_1; -.
DR InParanoid; K5WIJ9; -.
DR OrthoDB; 166885at2759; -.
DR Proteomes; UP000008370; Unassembled WGS sequence.
DR GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR Gene3D; 3.60.21.60; -; 1.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016266; POLE2.
DR PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
DR PIRSF; PIRSF000799; DNA_pol_eps_2; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR000799};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR000799};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR000799};
KW Reference proteome {ECO:0000313|Proteomes:UP000008370}.
FT DOMAIN 290..492
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
SQ SEQUENCE 538 AA; 61043 MW; A855A28539B1959B CRC64;
MADPKQRAII KVFRKYSHSL GPEALEFVEE ILERHEIPED QVEQSVEWIA KEYNKQDDAQ
MKVSLEVLQR VYDTFQEGSD MADGDFLDPE SHLYFIDAFE MPLWNWSTER SAFERALAPL
TGSGSADTRI SAIRNRLNII KQTILRNDHF SPSTIAARDR EHLLTLRSTK QLLGRAGQRF
LLFGMLSHSK EGKICLEDED GAVELDFSQL DQPSEGLFTE GCFALVEGDY TDEATLQIIA
IGHPPCESRE AAKSIYGHID FLGKGATTLA EDNQLATRLR EDWPDLRCFV LSDVWLDHPD
TMQGLKKLFD NCVENQFIPR LIVLCGNFSQ RGVAQGNSRE IRRYQDGFDS LAELIASYPV
FTRQTHFILV PGPRDITVNS ILPRKPIISS FTGKLKSKVP KLHLGSNPCR IKLCDQELVI
FREDLMARML RNLVGVKPDV REDDLKRYLV QSVLDQSHLM PLTTSIQSTL PEYDHTLRLY
PLPTAVVLAD KYDRYQMTYE GCHVFNPGSF LGNSFGFSAY TPACRESEEC VLGFDGDG
//
