ID K5WMB5_AGABU Unreviewed; 752 AA.
AC K5WMB5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Potassium channel domain-containing protein {ECO:0000259|Pfam:PF07885};
GN ORFNames=AGABI1DRAFT_131293 {ECO:0000313|EMBL:EKM76466.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM76466.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH971402; EKM76466.1; -; Genomic_DNA.
DR RefSeq; XP_007332909.1; XM_007332847.1.
DR AlphaFoldDB; K5WMB5; -.
DR GeneID; 18827404; -.
DR KEGG; abp:AGABI1DRAFT131293; -.
DR eggNOG; KOG1418; Eukaryota.
DR HOGENOM; CLU_382147_0_0_1; -.
DR InParanoid; K5WMB5; -.
DR OMA; HSRTHHE; -.
DR OrthoDB; 5010334at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.10.287.70; -; 1.
DR InterPro; IPR013099; K_chnl_dom.
DR PANTHER; PTHR11537:SF254; POTASSIUM VOLTAGE-GATED CHANNEL PROTEIN SHAKER; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF07885; Ion_trans_2; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 2.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 90..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 161..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 616..641
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 247..317
FT /note="Potassium channel"
FT /evidence="ECO:0000259|Pfam:PF07885"
FT REGION 28..82
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..528
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 752 AA; 85208 MW; 59C9A67CC9710521 CRC64;
MVLPAVFSLF FPWRSRLPNR LIRRPENDIE VSSPGAPISP SSSPHDANGK EIFTTHSNSS
FRRDRDQAPA SPDHHEQPDN SNANIRSLPL ISSIFVPFSI LLAVPGLTDH WYIRTNDQHQ
ILDFEPNPLY LRVMLGFSMA FAVIANLCLL VRLFEKMVRW MTIICIILLT LHDILDISVI
TIFTIKTQVD DGFILGQAFW ATLCSTIAAF MINITLVLDY LRTSGAERDE SGLTKKQRTL
AINMIGLLCY IAFGAAIHLA LISLSYIDAL YFTVVSILTV GLGDITPHTP GARIFTSLYT
AAGIVIIAIN IGLIRESLLE VIRHNMYARI HRRRKRRIKY RWEIALKWRL EHAGLPIWIP
ISKEEEREEE EAEAEAEEYH HYSGATGPTG KWRNWRPLNA IWLHTLGGLR NLKTRCSYKK
RHMRLNLRGL SDAQLQAAAM EAGAPLQELL PAYFHSRTHH EVYGYVGGEQ AMRTTPTHYR
MGMMITLLGD FAYSFTMGQH GSSRRIKDDY PGQLDNADDD SGGDGLALDE PQMEERRHFV
ARIVAALACT QLSRKIIRNR SARPFFRPQK AGPTGYRFIF VSLLSLRSDM VGKYFFSGIS
EAPYDFHKGD PVPKTAAGRS IFVGWALCGV GTMTILISLL ADRYTEEYKR IISDTQSMKP
EGLPPTKRTQ DTTRMTIVPP TPPIMRNHDD AVFGNQELLS RVDTLKELIV DEGLFREGKL
LHTLESELQN MLSHIRLSRR KSSNGEHLWD ET
//
