ID K5WN38_AGABU Unreviewed; 854 AA.
AC K5WN38;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=BHLH domain-containing protein {ECO:0000259|PROSITE:PS50888};
GN ORFNames=AGABI1DRAFT_108591 {ECO:0000313|EMBL:EKM76736.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM76736.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JH971400; EKM76736.1; -; Genomic_DNA.
DR RefSeq; XP_007332638.1; XM_007332576.1.
DR AlphaFoldDB; K5WN38; -.
DR STRING; 597362.K5WN38; -.
DR GeneID; 18822590; -.
DR KEGG; abp:AGABI1DRAFT108591; -.
DR eggNOG; ENOG502S7T4; Eukaryota.
DR HOGENOM; CLU_350887_0_0_1; -.
DR InParanoid; K5WN38; -.
DR OMA; PWLGAYN; -.
DR OrthoDB; 1334653at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR PANTHER; PTHR15741; BASIC HELIX-LOOP-HELIX ZIP TRANSCRIPTION FACTOR; 1.
DR PANTHER; PTHR15741:SF38; BHLH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00010; HLH; 1.
DR SMART; SM00353; HLH; 1.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR PROSITE; PS50888; BHLH; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 632..728
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 116..152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 174..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..335
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 677..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..140
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 468..488
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 533..556
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..635
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 854 AA; 89293 MW; 50C20BB3694F3DC8 CRC64;
MSFQSSPSPS AGSQQQTNSP MPPSSSLQMQ MNLMQNLMQF QNVGEQMLGM SGQQTQFDGS
PSMAYNPPAA LVEQQFKINQ LQQLQQLQNQ IFQHQIALIS GQSILPAGHS MNRNDFSSNS
LPLSAMKDQS FTSTSPHNSY PGLPTPGPST EIRPRDSPME FVPPMVLGAD SLFDPPISPQ
STHDTSHISY PHSHSSGTPH FHAHTAPPQV VFDIRSEMTP NSSGADGLSS GSLSNVPLLS
NGADNDLDIS PLTSPWLGAG SHQRSSVGTD SGLHPHHVRS ASFSHLGRSG SKRPADRGCS
GDLNSAHGMF ESEPARKKHS PDSPSAPRGM NSQQQYQHMT PLTLLPQPNS PLSSPISPLT
TAINATNLVT GTGTCSSSSS ASGTNSQRRT YRGSMSTGNT PLLRGQRSRV SSNTRGQANN
NSSNNTSTSL TGTPSSASIG NGAGTFVADT PSPVDLAMPP PAPPGHVMNS SPSGSGSGSG
SNSNQDMDGM GPGGVLLPVT PASIMKLGKL GPSNNNHNND GDGGGHASVP RSWPGEPRDD
KKGGGAGEKD KDNGGGKGNR NGSGSAAGGA PTSIAASRTR RNTASTTAAT GGVSGSGLKT
ILPANSSYSP LISASAGVSS RSNDQDSQQQ LPRKTSHKAA EQKRRDSLKT AYDELRTLLP
PIPLSSDMDE SALANGFGIP GAWPPRSSSS LPGSLPPRGP PKTGAEGPNK GVSKLQLLIC
GNEFIRVLKK RVERRDEEII KLRDEVGKLR CLVRDMKLGG DSNDMEEDRR RHNEGDYGIR
GSFAGGSFDF DWDLDLEKDL DAVEMHNSDA NEACGNIGGM MGGGMGMGTG VVNVGLSVNA
LGSLGEQPDQ EEED
//
