ID K5WYT8_PHACS Unreviewed; 1074 AA.
AC K5WYT8;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 22-FEB-2023, entry version 42.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=PHACADRAFT_173831 {ECO:0000313|EMBL:EKM55672.1};
OS Phanerochaete carnosa (strain HHB-10118-sp) (White-rot fungus) (Peniophora
OS carnosa).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Polyporales; Phanerochaetaceae; Phanerochaete.
OX NCBI_TaxID=650164 {ECO:0000313|EMBL:EKM55672.1, ECO:0000313|Proteomes:UP000008370};
RN [1] {ECO:0000313|EMBL:EKM55672.1, ECO:0000313|Proteomes:UP000008370}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HHB-10118-sp {ECO:0000313|EMBL:EKM55672.1,
RC ECO:0000313|Proteomes:UP000008370};
RX PubMed=22937793; DOI=10.1186/1471-2164-13-444;
RA Suzuki H., MacDonald J., Syed K., Salamov A., Hori C., Aerts A.,
RA Henrissat B., Wiebenga A., vanKuyk P.A., Barry K., Lindquist E.,
RA LaButti K., Lapidus A., Lucas S., Coutinho P., Gong Y., Samejima M.,
RA Mahadevan R., Abou-Zaid M., de Vries R.P., Igarashi K., Yadav J.S.,
RA Grigoriev I.V., Master E.R.;
RT "Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P.
RT chrysosporium, to elucidate the genetic basis of the distinct wood types
RT they colonize.";
RL BMC Genomics 13:444-444(2012).
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; JH930472; EKM55672.1; -; Genomic_DNA.
DR RefSeq; XP_007395991.1; XM_007395929.1.
DR AlphaFoldDB; K5WYT8; -.
DR STRING; 650164.K5WYT8; -.
DR GeneID; 18909652; -.
DR KEGG; pco:PHACADRAFT_173831; -.
DR HOGENOM; CLU_011906_0_0_1; -.
DR InParanoid; K5WYT8; -.
DR OrthoDB; 169519at2759; -.
DR Proteomes; UP000008370; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 2.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008370};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 34..100
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REGION 1040..1074
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1040..1057
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1074 AA; 122503 MW; 4006D2BBE4FECAA3 CRC64;
MEGILDFSRE FDVSLMDKVA MAFYAGSGQE QQMAQQVLTQ FQEHPDAWTR VPDILERSSF
PQAKYIGLQI LEKLILTRWK SLPEGQRQGI RNFIVGITVK IASDEATLRR EKTYVNKLNL
ALVQILKQEW PHNWPTFISE LVESSKTNLS LCENNMVILR LLSEEVFDFS AEQMTQAKVK
NLKNQMCGEF SEIFKLCSEI LEEAQKTSLI RATLETLLRF LNWIPLGYIF ETTIIDLLLN
RFLEAPEFRN VTLKCLAEIA ALNVGPEYDP KFVILFAMVM TSVNRMIPPS TNIAQAYANA
GDAGQELVLN LALFLCNFLS NHLRAVETEQ NRDVLLNAHL YLVKISQVDE REIFKICLEY
WLKLVAELYE EIQSLPIGDS GLLMGLSLGG SQSMLNGMNL RKTIYSDVLS NLRLVVIEKM
VKPEEVLIVE NEEGEIVREF MKESDTIVLY KQMRELLVYL THLDVQDTET ILTEKLAKQV
DGSEWSWQNL NTLCWAIGSI SGAMNEETEK RFLVTVIKDL LGLCEIKRGK DNKAVVASDI
MYIVGQYPRF LKAHWKFLKT VVNKLFEFMH ETHEGVQDMA CDTFIKIAQK CRRHFVMQQA
GETEPFVDEI LRMLHRITVD LSPQQVHTFY EAVGYMISAQ PNKPQQEKLI AKLMELPNNA
WDSLMAQAAQ NMDVLGNMDN IKILSNVLKT NVAACTSIGA FYLPQIARIF LDMLGLYKAV
SGIISETIAR EGLIATKTPK VRQLRTIKKE VLKLMETFIR KAEDLETVNG NFMPPLLDAI
LGDYNRNVPA ARDAEVLNVM ATIISRLGPL LTPQVPAILD AVFEPTLNMI NQDFAEFPEH
RVGFFKLLRA INLNCFPALL TIPPQQFKLF MDSIIWAIKH TMRDIAETGL NLCLEVINNF
ATADSGVANA FFQQYFLSIM QDIFYVLTDT DHKSGFKLQS MLLARMFQLV ETNQITVPLF
DPSQVPDPSI NNTVFLREYT ANLLKSAFPH VQNAQIQTFV MSLGEFHNDI NRFKLALRDF
LIQLKEFSAG DNAELYLEEK EDEAQRKAQE EREAAMRIPG MLKPSQIEDK DEDI
//
