ID K5WZI3_AGABU Unreviewed; 442 AA.
AC K5WZI3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 08-NOV-2023, entry version 39.
DE RecName: Full=O-methyltransferase domain-containing protein {ECO:0000259|Pfam:PF00891};
GN ORFNames=AGABI1DRAFT_109107 {ECO:0000313|EMBL:EKM76027.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM76027.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
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DR EMBL; JH971406; EKM76027.1; -; Genomic_DNA.
DR RefSeq; XP_007333399.1; XM_007333337.1.
DR AlphaFoldDB; K5WZI3; -.
DR GeneID; 18822688; -.
DR KEGG; abp:AGABI1DRAFT109107; -.
DR eggNOG; KOG3178; Eukaryota.
DR HOGENOM; CLU_005533_0_1_1; -.
DR InParanoid; K5WZI3; -.
DR OMA; VGNICIN; -.
DR OrthoDB; 724039at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0008171; F:O-methyltransferase activity; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR016461; COMT-like.
DR InterPro; IPR001077; O_MeTrfase_dom.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR43712:SF2; O-METHYLTRANSFERASE CICE; 1.
DR PANTHER; PTHR43712; PUTATIVE (AFU_ORTHOLOGUE AFUA_4G14580)-RELATED; 1.
DR Pfam; PF00891; Methyltransf_2; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51683; SAM_OMT_II; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 190..420
FT /note="O-methyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00891"
SQ SEQUENCE 442 AA; 49258 MW; ED471FF4EFCA0EAE CRC64;
MDSTTSRIDE LRGLMVLIGN AVDILEHDIS QRKLASKEQP SDAELRSSVC TVEAACAQLC
SLVARPGDVL ANKFLAFYEP ACLQVVLSNK IPDILQEYPS GAHISELEKR TGISEGKLCR
ILRFLAAKHV FQEVGANTFA NNHLSRELVS SNPLSSLGLC ITNEMFKAGS SLGDVLNDPE
RRASTSPLDT AFSKYFGMKT LFDYYAVSSS EQNKLAFHFD KGMIGWGSVM EIDSLIPGIP
WNTLPKGTSV CDVGGGVGNI CINLAKHYPT WKLVLQDLPK PIDNAEKKIW PERCPEAIAE
NRIEFIPLDF LKGSPKEGCD IYYLKNILHS WSDEDCIKII GNVRRAMGPS SRLFVHEFVV
RPGYRIPKEE ARFVQAPEPL LPNFGEGRIR QYSMDINMMA LFNSAERTLD DFIQLGQSAG
LKFVKLWETG ELGIVEFIQQ HH
//