ID K5X367_AGABU Unreviewed; 603 AA.
AC K5X367;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE RecName: Full=SET domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AGABI1DRAFT_108076 {ECO:0000313|EMBL:EKM77573.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM77573.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
CC -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|ARBA:ARBA00004286}.
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DR EMBL; JH971395; EKM77573.1; -; Genomic_DNA.
DR RefSeq; XP_007331836.1; XM_007331774.1.
DR AlphaFoldDB; K5X367; -.
DR STRING; 597362.K5X367; -.
DR GeneID; 18822512; -.
DR KEGG; abp:AGABI1DRAFT108076; -.
DR eggNOG; KOG1082; Eukaryota.
DR HOGENOM; CLU_020840_8_2_1; -.
DR InParanoid; K5X367; -.
DR OMA; MYLEREY; -.
DR OrthoDB; 5481936at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0005694; C:chromosome; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0042054; F:histone methyltransferase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR InterPro; IPR007728; Pre-SET_dom.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR PANTHER; PTHR46223:SF3; HISTONE H3 (LYS9) METHYLTRANSFERASE-RELATED; 1.
DR PANTHER; PTHR46223; HISTONE-LYSINE N-METHYLTRANSFERASE SUV39H; 1.
DR Pfam; PF05033; Pre-SET; 1.
DR Pfam; PF00856; SET; 1.
DR SMART; SM00468; PreSET; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF82199; SET domain; 1.
DR PROSITE; PS50867; PRE_SET; 1.
DR PROSITE; PS50280; SET; 1.
PE 4: Predicted;
KW Chromosome {ECO:0000256|ARBA:ARBA00022454};
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 356..425
FT /note="Pre-SET"
FT /evidence="ECO:0000259|PROSITE:PS50867"
FT DOMAIN 428..560
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 148..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..282
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 68025 MW; B1675F21015AA6F1 CRC64;
MSESDSSGSY IDESFWRNSP SPEANDEMGE EGKEWYFEVV GEEVDADGDV RQVDWDGWKR
ADGTTQTWQR MNPNLTREWR VMQRRRREDV LKDSIDIDLG AFSGVDIHND ETRLRAQAYK
DKLALRRRYS PKLEEQMAKL LAEKLGDGAE LDNHSSPSSA VPTTPAGRGL RLSTIRQQQQ
KSPMPQRRGP IQGQDDANKS QTPTSSLRPS QSARTMSASS SRSNSRPSAP PTQINYPHSS
QSKNSTATPI RDPQDRTARK RKVSESEVDQ MGEQQRERST IVTADKGKAP MNKILLRLEC
SLKWTKIARA AGAAPITIVN DVDDEEIPFL ALGFCYLEKG YQYPPYIDPP KLDFQVGCDC
KRCGDASQCD CQSVSELVDD DGQKIFAYTK TGLFSFNVPR HVEVVECNET CRCGPGCINR
VSQRPRDVPL EIFKTRGKGW GVRAAVDIVR GKVLGMYSGK LLSRQVADKM TNSRDGEYIF
DLDGQEDLKD GDDDELMTNK YSIDSRMHGN WTHFVNHSCT PNMIIYLAVY DTLPGTNCPY
LTFVAQEFIK AGTELTMDYD PAFADTMESD DMIWHLNEML HAVAFKPHFD LHQTRDEAMI
VCD
//
