ID K5X7S0_AGABU Unreviewed; 656 AA.
AC K5X7S0;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN ORFNames=AGABI1DRAFT_40786 {ECO:0000313|EMBL:EKM79027.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM79027.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC in alpha-L-rhamnosides.; EC=3.2.1.40;
CC Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR EMBL; JH971391; EKM79027.1; -; Genomic_DNA.
DR RefSeq; XP_007330322.1; XM_007330260.1.
DR AlphaFoldDB; K5X7S0; -.
DR STRING; 597362.K5X7S0; -.
DR GeneID; 18829371; -.
DR KEGG; abp:AGABI1DRAFT40786; -.
DR eggNOG; ENOG502QWE4; Eukaryota.
DR HOGENOM; CLU_007933_3_0_1; -.
DR InParanoid; K5X7S0; -.
DR OMA; GYFHCDD; -.
DR OrthoDB; 67137at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR035396; Bac_rhamnosid6H.
DR InterPro; IPR035398; Bac_rhamnosid_C.
DR PANTHER; PTHR34987:SF4; ALPHA-L-RHAMNOSIDASE C-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR34987; C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED; 1.
DR Pfam; PF17389; Bac_rhamnosid6H; 1.
DR Pfam; PF17390; Bac_rhamnosid_C; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..656
FT /note="alpha-L-rhamnosidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003890152"
FT DOMAIN 273..459
FT /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT /evidence="ECO:0000259|Pfam:PF17389"
FT DOMAIN 573..632
FT /note="Alpha-L-rhamnosidase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF17390"
SQ SEQUENCE 656 AA; 71236 MW; A979D96BD3F8A096 CRC64;
MLTSFIAFTL IAAGAFGLAP PGPWDRFNIA PKDRISRPTI IHSIEGNVRN ADALIGSGTA
TFNGNGSFVT LDFGLEVGGR VFFDVVHSTG DARLSLSFTE SPEFISPLKS DDSCQQIFTM
DGDGVQSLPV PLGTGKFMQT VRQQRGGFRY MTIVSHSDGP IGVAGVGVEN TFMPHWDDFR
AYTGYFFTKD PNFHDSDFLT KLWYSGAYTV QTNTIDPRSA RQLPCLHWAN NATGGLVDGP
ILADGAKRDR SPGDMGISSH TELVALNDML PSKNALLVMF ATQDPATGSL QYSGPPINAK
GSDTYIAWSL IGTHNVWLYT GDIEFVHDVW SNYTKALAFL ESQVDETGLM NVPQEFSQDW
GRDGGQGRNI AANVLLYRSL VTASELANEM GEVRLSKAYA ANATALKSDI NNLLWDSTAE
MFRDNDSSDL IPQDGNAMAV LFNVTQTREQ VKAISKGLTQ FWTDIGPLSP ELNDTIIPFV
GGFEVQAHFI ADEGERALDL IHREWGYMLY TNLSVQSTLL EGFTANGSLG YRAAAGYDFD
HAFTSHSHGW ATGPTPAMTF HILGLGITSP QGKTWSINPI LSGLQFAEGG LETGLGWFGV
KWEVSDDMLT VEISTPTGTS GTVRLPGKGP VTVDGIAQEE TNVRLRGGEH VLKRHV
//
