ID K5XK55_AGABU Unreviewed; 560 AA.
AC K5XK55;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Magnesium transporter {ECO:0008006|Google:ProtNLM};
GN ORFNames=AGABI1DRAFT_66982 {ECO:0000313|EMBL:EKM83913.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM83913.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH971385; EKM83913.1; -; Genomic_DNA.
DR RefSeq; XP_007325172.1; XM_007325110.1.
DR AlphaFoldDB; K5XK55; -.
DR STRING; 597362.K5XK55; -.
DR GeneID; 18830625; -.
DR KEGG; abp:AGABI1DRAFT66982; -.
DR eggNOG; ENOG502RX8H; Eukaryota.
DR HOGENOM; CLU_007127_11_2_1; -.
DR InParanoid; K5XK55; -.
DR OMA; NMSADWI; -.
DR OrthoDB; 1358357at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR CDD; cd12829; Alr1p-like; 1.
DR Gene3D; 3.30.460.20; CorA soluble domain-like; 1.
DR Gene3D; 1.20.58.340; Magnesium transport protein CorA, transmembrane region; 1.
DR InterPro; IPR044089; Alr1-like.
DR InterPro; IPR045861; CorA_cytoplasmic_dom.
DR InterPro; IPR002523; MgTranspt_CorA/ZnTranspt_ZntB.
DR PANTHER; PTHR21535; MAGNESIUM AND COBALT TRANSPORT PROTEIN/MITOCHONDRIAL IMPORT INNER MEMBRANE TRANSLOCASE SUBUNIT TIM8; 1.
DR PANTHER; PTHR21535:SF90; TRANSPORTER, PUTATIVE-RELATED; 1.
DR Pfam; PF01544; CorA; 2.
DR SUPFAM; SSF143865; CorA soluble domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 491..512
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 524..549
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 19..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 105..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 115..129
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 560 AA; 63571 MW; 63EA0EAE7A6605EB CRC64;
MKAIEESRQI PRQFILYLPP PPKHPQSSRC TARGHDDGDY GSKKVIRTSS LSLVLDQLGE
RLKRTTRGRR LHGKFGVGTL PLHQSRKVTY KPQGQSVIIA TESGSATPLQ GSNIRRSDKG
KHREGSNHLH HLQATSRAPR AWFLDVSSPT WGDLKAIGKL LHLHPLTLED ILQQEPREKL
DLFQKLGYYF ISFRAIETRD DREKFHQKIH KMDGQLETAA NHDGTVRETN VYLVVFDEGI
CCFHYNDIAE HTDRVRNRIA LLEEVANMSA DWIAHGILDS IVDSFFPYLE NIEKEVMAIE
ELVFSANAAY TSTTPPTQTN VESFEKPQIS PLSETLSFSE KSSVGGSMRP HFAVPKWTLQ
LLSRRIRRFF KRVWKRMVNS PVATPTATAL TLRQMARTRR LVTSLGRLLA SKSEVVAQIK
KRLLKTGTLD PSVNAEELEV AMYMGDIQDH ILTFQHSLNH YERMLSQSHP AYLSQLRATF
ASSKSGTDKS LFYLTSVSIA VICVQVVMGN FSMNINVPRD GTGYRIFGVV FSLAIIVLFI
YVNIVRYWWK QAGKTRRALL
//
