ID K5Y2L7_AGABU Unreviewed; 573 AA.
AC K5Y2L7;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=Nucleolar protein 58 {ECO:0000256|ARBA:ARBA00020379};
GN ORFNames=AGABI1DRAFT_112235 {ECO:0000313|EMBL:EKM82110.1};
OS Agaricus bisporus var. burnettii (strain JB137-S8 / ATCC MYA-4627 / FGSC
OS 10392) (White button mushroom).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Agaricus.
OX NCBI_TaxID=597362 {ECO:0000313|EMBL:EKM82110.1, ECO:0000313|Proteomes:UP000008493};
RN [1] {ECO:0000313|Proteomes:UP000008493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JB137-S8 / ATCC MYA-4627 / FGSC 10392
RC {ECO:0000313|Proteomes:UP000008493};
RX PubMed=23045686; DOI=10.1073/pnas.1206847109;
RA Morin E., Kohler A., Baker A.R., Foulongne-Oriol M., Lombard V., Nagy L.G.,
RA Ohm R.A., Patyshakuliyeva A., Brun A., Aerts A.L., Bailey A.M.,
RA Billette C., Coutinho P.M., Deakin G., Doddapaneni H., Floudas D.,
RA Grimwood J., Hilden K., Kuees U., LaButti K.M., Lapidus A., Lindquist E.A.,
RA Lucas S.M., Murat C., Riley R.W., Salamov A.A., Schmutz J., Subramanian V.,
RA Woesten H.A.B., Xu J., Eastwood D.C., Foster G.D., Sonnenberg A.S.,
RA Cullen D., de Vries R.P., Lundell T., Hibbett D.S., Henrissat B.,
RA Burton K.S., Kerrigan R.W., Challen M.P., Grigoriev I.V., Martin F.;
RT "Genome sequence of the button mushroom Agaricus bisporus reveals
RT mechanisms governing adaptation to a humic-rich ecological niche.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:17501-17506(2012).
CC -!- FUNCTION: Required for pre-18S rRNA processing. May bind microtubules.
CC {ECO:0000256|ARBA:ARBA00024837}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the NOP5/NOP56 family.
CC {ECO:0000256|ARBA:ARBA00009211}.
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DR EMBL; JH971387; EKM82110.1; -; Genomic_DNA.
DR RefSeq; XP_007327844.1; XM_007327782.1.
DR AlphaFoldDB; K5Y2L7; -.
DR STRING; 597362.K5Y2L7; -.
DR GeneID; 18823557; -.
DR KEGG; abp:AGABI1DRAFT112235; -.
DR eggNOG; KOG2572; Eukaryota.
DR HOGENOM; CLU_015495_5_2_1; -.
DR InParanoid; K5Y2L7; -.
DR OMA; KGKMARI; -.
DR OrthoDB; 5489581at2759; -.
DR Proteomes; UP000008493; Unassembled WGS sequence.
DR GO; GO:0031428; C:box C/D RNP complex; IEA:InterPro.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0032040; C:small-subunit processome; IEA:InterPro.
DR GO; GO:0030515; F:snoRNA binding; IEA:InterPro.
DR GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.4070; -; 1.
DR Gene3D; 1.10.246.90; Nop domain; 1.
DR InterPro; IPR045056; Nop56/Nop58.
DR InterPro; IPR012974; NOP58/56_N.
DR InterPro; IPR042239; Nop_C.
DR InterPro; IPR002687; Nop_dom.
DR InterPro; IPR036070; Nop_dom_sf.
DR InterPro; IPR012976; NOSIC.
DR PANTHER; PTHR10894; NUCLEOLAR PROTEIN 5 NUCLEOLAR PROTEIN NOP5 NOP58; 1.
DR PANTHER; PTHR10894:SF1; NUCLEOLAR PROTEIN 58; 1.
DR Pfam; PF01798; Nop; 1.
DR Pfam; PF08156; NOP5NT; 1.
DR SMART; SM00931; NOSIC; 1.
DR SUPFAM; SSF89124; Nop domain; 1.
DR PROSITE; PS51358; NOP; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008493}.
FT DOMAIN 285..409
FT /note="Nop"
FT /evidence="ECO:0000259|PROSITE:PS51358"
FT REGION 470..573
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..490
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 498..521
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 529..552
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 573 AA; 63567 MW; DE5E2884E071C818 CRC64;
MLVLYETALG YCLFKVTDSA KLEKADLWKE FESPEQTNKL LKLKALHRFT STATAVEDIT
ALQEGKLGKG LKKFLTDEVV NKGKGKESLL VVDSNLGRSI SKKLSINISV PPEGSNEIWR
GIRNQLAALL DGLDPKDLAT MSLGLSHSLS RFKVKFSPDK VDTMVVQAVA LLDDLDKEIN
IYAMRVKEWY GWHFPEMAKI ISDNIAYAKV IRHMGFRTNA ASTDFSSLLP EDLEAVLKAA
AEISMGTEIS DSDIAHINSL CDQVISISSY RSQLAEYLRN RMNAIAPNLT ALVGELVGAR
LISHAGSLLS LAKYPASTVQ ILGAEKALFR ALKTKHDTPK YGLIYHASLI GQAPSKLKGK
MARMVATKAA LSIRVDALTD SNGKSEDNAA SIGVENRAKL ESRLRALEHQ LELGVTNQFS
QNNHKQQARF SMTGETKTYN TKEDLVDFVS TQRENPMEAA VQAVLNVKEE KKKAKEEKKA
KKKAKENQED QMDVDEEGEQ EKMSKEDKKE KKRKRRESDM LPTAENGSPA KEETEEERRA
RKEARKAARK AEKAAAAAAS TDSPKKKKKK NSE
//
