ID K5YUK6_9PROT Unreviewed; 354 AA.
AC K5YUK6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Naringenin-chalcone synthase {ECO:0000313|EMBL:EKM98537.1};
GN ORFNames=MXAZACID_15034 {ECO:0000313|EMBL:EKM98537.1};
OS Acidocella sp. MX-AZ02.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acidocella.
OX NCBI_TaxID=1214225 {ECO:0000313|EMBL:EKM98537.1, ECO:0000313|Proteomes:UP000006217};
RN [1] {ECO:0000313|EMBL:EKM98537.1, ECO:0000313|Proteomes:UP000006217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX-AZ02 {ECO:0000313|EMBL:EKM98537.1,
RC ECO:0000313|Proteomes:UP000006217};
RX PubMed=23405365;
RA Servin-Garciduenas L.E., Garrett R.A., Amils R., Martinez-Romero E.;
RT "Genome Sequence of the Acidophilic Bacterium Acidocella sp. Strain MX-
RT AZ02.";
RL Genome Announc. 1:E00041-12(2013).
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Chalcone/stilbene
CC synthases family. {ECO:0000256|ARBA:ARBA00005531}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKM98537.1}.
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DR EMBL; AMPS01000209; EKM98537.1; -; Genomic_DNA.
DR RefSeq; WP_008495317.1; NZ_JH976210.1.
DR AlphaFoldDB; K5YUK6; -.
DR STRING; 1214225.MXAZACID_15034; -.
DR PATRIC; fig|1214225.3.peg.2912; -.
DR HOGENOM; CLU_034992_0_2_5; -.
DR Proteomes; UP000006217; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00831; CHS_like; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR012328; Chalcone/stilbene_synt_C.
DR InterPro; IPR001099; Chalcone/stilbene_synt_N.
DR InterPro; IPR011141; Polyketide_synthase_type-III.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11877; HYDROXYMETHYLGLUTARYL-COA SYNTHASE; 1.
DR PANTHER; PTHR11877:SF46; TYPE III POLYKETIDE SYNTHASE A; 1.
DR Pfam; PF02797; Chal_sti_synt_C; 1.
DR Pfam; PF00195; Chal_sti_synt_N; 1.
DR PIRSF; PIRSF000451; PKS_III; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006217}.
FT DOMAIN 4..212
FT /note="Chalcone/stilbene synthase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00195"
FT DOMAIN 224..349
FT /note="Chalcone/stilbene synthase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02797"
FT ACT_SITE 150
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000451-1"
SQ SEQUENCE 354 AA; 37744 MW; 6EF9D8F221BAE4A3 CRC64;
MTQAYINRIG TARPPHDVHA AFQDYTARGL PDERQRALFH RMARRAGISH RYSVLHQDGM
VEAAAPTPGF YRRGAFPGTA ARMRTYAAHA PALAEQAVSQ LDLQGRAQEI THLVVASCTG
FMAPGLDQIL AARLGLRVDL QRTMVGFMGC AAAVPALRIA QAAVLADPAA RVLVVNLELC
TLHMQETDAL EVALTFLLFG DGATAALVTA EPHGFALEDF RSVLIPDSED FISWHVGDQG
FVMHLSGQVP GRIAAALRAA PDFILRGEGT QALQLWAVHG GGRSVLDAVE GAFGLEETAL
APSRAVLDAH GNMSSATIMF VLAGMLKTAP PGQRGLAMAF GPGMVTETFR FTAR
//
