ID K5YZ29_9PROT Unreviewed; 860 AA.
AC K5YZ29;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=RND efflux transporter {ECO:0000313|EMBL:EKN00008.1};
GN ORFNames=MXAZACID_07381 {ECO:0000313|EMBL:EKN00008.1};
OS Acidocella sp. MX-AZ02.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Acetobacteraceae; Acidocella.
OX NCBI_TaxID=1214225 {ECO:0000313|EMBL:EKN00008.1, ECO:0000313|Proteomes:UP000006217};
RN [1] {ECO:0000313|EMBL:EKN00008.1, ECO:0000313|Proteomes:UP000006217}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MX-AZ02 {ECO:0000313|EMBL:EKN00008.1,
RC ECO:0000313|Proteomes:UP000006217};
RX PubMed=23405365;
RA Servin-Garciduenas L.E., Garrett R.A., Amils R., Martinez-Romero E.;
RT "Genome Sequence of the Acidophilic Bacterium Acidocella sp. Strain MX-
RT AZ02.";
RL Genome Announc. 1:E00041-12(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKN00008.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AMPS01000100; EKN00008.1; -; Genomic_DNA.
DR RefSeq; WP_008493596.1; NZ_JH976207.1.
DR AlphaFoldDB; K5YZ29; -.
DR STRING; 1214225.MXAZACID_07381; -.
DR PATRIC; fig|1214225.3.peg.1429; -.
DR HOGENOM; CLU_009099_0_0_5; -.
DR Proteomes; UP000006217; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR017841; Hopanoid_biosynth_HpnN.
DR InterPro; IPR004869; MMPL_dom.
DR NCBIfam; TIGR03480; HpnN; 1.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF2; MEMBRANE PROTEIN SCO6666-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006217};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 267..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 450..471
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 714..730
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 737..757
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 763..783
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 795..819
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 831..851
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 229..423
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 660..857
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
SQ SEQUENCE 860 AA; 90545 MW; E53D1779460DA10E CRC64;
MRLINSIVAT ASRHAVLCVL LFLVLGGLGL GYTARHLAID TDTDHLFAAS LAWRQAQIAE
DKNFPQFNDL IVAVVRADTP EEAKETATAL NAALQADTAH FKDSSYPSGD RFYTDEGLLL
LPTDQLAKLL NQIVAAQPFL GQLAADPSAR GLLDGLALIT QGVQAGANIS PYNQAIAGVR
ANLQAAANGK PVPLSWQSLI MAGAPGQGGA EFVLAHPKLQ QGTLQPGGEA TKALMAIAKT
LPDVKAGRAT VNYTGQIPLS DEQFASLTHG LVLGGIISVV LIALWLYLAL RSWRLILPIL
LTLVMGLALT MSYAAIVVRT INLISVAFAI LFIGLAVDFA IQYCVRLRAV RLMEPELGPA
LRETSRLAGA QIALAATATA CGFLAFAPTP FVGVAELGEI AGAGMFIAFF CTISFLPALL
RLFRPHPETE SVALPGGAKA DHVLRRHRRA VLGLFGALAL AGLWGAVTLR FDANPLDTKD
PNTESMRTIR SLLADPQTNP FYADALAPNL DAARALADKL GTLKEVSQAI SGATFVPQDQ
PQKLAMLAQA QTILAPTLLA AATPPKQPVT AQEIRDAMAK TIAAITNVQA KLPKGSELLG
IASVLKQLQG EDDARIMAMN EAITRFLPLE LQNLTRALQA KPITQDNLPA SIKADWFLPD
GQVRVEAFPT AAAQTTKGLY AFSKAVLAAA PNAGGPAIST IATAGTILSS FKEAAILAFI
AIAVILLAVF RNLRDSLLVL AALALSALLT ALFARMAGMS INYANIIALP LLLGVGVSFN
VYFVMNFRSG MRNFLASATA RAVLFSALTT ATAFGSLAAS ADRGTASMGD LLFLSLAAVL
VSTFIFLPAL LHTLADARKA
//
