ID K5Z4N4_9BACT Unreviewed; 365 AA.
AC K5Z4N4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:EKN10544.1};
GN ORFNames=HMPREF1077_01795 {ECO:0000313|EMBL:EKN10544.1};
OS Parabacteroides johnsonii CL02T12C29.
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC Parabacteroides.
OX NCBI_TaxID=999419 {ECO:0000313|EMBL:EKN10544.1, ECO:0000313|Proteomes:UP000001218};
RN [1] {ECO:0000313|EMBL:EKN10544.1, ECO:0000313|Proteomes:UP000001218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CL02T12C29 {ECO:0000313|EMBL:EKN10544.1,
RC ECO:0000313|Proteomes:UP000001218};
RG The Broad Institute Genome Sequencing Platform;
RA Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Parabacteroides johnsonii CL02T12C29.";
RL Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKN10544.1}.
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DR EMBL; AGZP01000016; EKN10544.1; -; Genomic_DNA.
DR RefSeq; WP_008156344.1; NZ_JH976466.1.
DR AlphaFoldDB; K5Z4N4; -.
DR PATRIC; fig|999419.3.peg.1838; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_1_2_10; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000001218; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 2.40.50.100; -; 1.
DR Gene3D; 1.10.287.470; Helix hairpin bin; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30469; MULTIDRUG RESISTANCE PROTEIN MDTA; 1.
DR PANTHER; PTHR30469:SF36; SLL0180 PROTEIN; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001218};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 81..280
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT COILED 150..177
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 365 AA; 40192 MW; 7F9AA96F4C548AA3 CRC64;
MTKRVKWSVT AAIVLMIAGM IAYPQIKSRM KASKDAAEVV PTAGSQVRKQ VLNINAEVLK
YQSLTDKTIV TGSTIPDEEV DLSFESSGKI VAIYFTEGTH VKSGDLLAKI NDKPLQAELK
KLEAQVPLAK DRVYRQHTLL EKDAVSQEAY EQVATEYEKL MADIELVKAN IAQTELRAPF
DGIIGLRNVS EGAYASPSTV ITKLTKISPL KIEFSVPERY SADIKDGTPI VFRMNSSVGM
MQDYKATVYA VESKIDEATR SLKVRATYLN RDESIVPGRY TSVEITRRDI KDALAIPSEA
LIPEMGKNIV YLYKSGVAEP AEIILGLRTE SQVQVLKGLN VGDTVITSGV MQLRTGMKVS
IDNLK
//
