ID   K5Z6L7_9BACT            Unreviewed;       573 AA.
AC   K5Z6L7;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|SMART:SM00534};
GN   ORFNames=HMPREF1077_01472 {ECO:0000313|EMBL:EKN11214.1};
OS   Parabacteroides johnsonii CL02T12C29.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC   Parabacteroides.
OX   NCBI_TaxID=999419 {ECO:0000313|EMBL:EKN11214.1, ECO:0000313|Proteomes:UP000001218};
RN   [1] {ECO:0000313|EMBL:EKN11214.1, ECO:0000313|Proteomes:UP000001218}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CL02T12C29 {ECO:0000313|EMBL:EKN11214.1,
RC   ECO:0000313|Proteomes:UP000001218};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA   Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA   Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA   Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Parabacteroides johnsonii CL02T12C29.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKN11214.1}.
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DR   EMBL; AGZP01000015; EKN11214.1; -; Genomic_DNA.
DR   AlphaFoldDB; K5Z6L7; -.
DR   PATRIC; fig|999419.3.peg.1507; -.
DR   eggNOG; COG0249; Bacteria.
DR   HOGENOM; CLU_030717_1_0_10; -.
DR   OrthoDB; 9802448at2; -.
DR   Proteomes; UP000001218; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR   InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR   InterPro; IPR045076; MutS_family.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR   PANTHER; PTHR11361:SF99; DNA MISMATCH REPAIR PROTEIN-RELATED; 1.
DR   Pfam; PF00488; MutS_V; 1.
DR   SMART; SM00534; MUTSac; 1.
DR   SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001218};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        190..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        286..309
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          382..568
FT                   /note="DNA mismatch repair proteins mutS family"
FT                   /evidence="ECO:0000259|SMART:SM00534"
SQ   SEQUENCE   573 AA;  65452 MW;  C6C56EE34B22CFB6 CRC64;
     MKVCLILCFL NALTSSKKKF AQTYGKNRDI NHDLCLNLSL SPIQTLQMGR RARSYAGEIK
     SETFNLTDIS AYFRYRKEVE RDNLLSDQTY SDLGVEELFT FADRTVSRVG QQYLYQTLRS
     VPQAAGEISR HEEIIRHLQT DSHLRERLAK TLSHLRDTEA YSIVRLLADE QPATSTNRKV
     TFAILKCLPA LFLLLYLLLH IPACGLFFLV AIILNAGIHY TYKPKSIDYI YSVPQLIKLL
     GTAEKLCKIP ELSKLATDIP DALATLKPIR KTALFLRMEN KLQSDMAALA WLCTELLHIF
     FLTEPFSFLQ SVSILRNKCR EIETVYRFVG LTDCLLSVCF LREHLPYYCL PGRPEERHRL
     ASQEMYHPLI EDCVANSIDI QDRSVLLNGS NMSGKTTFIR IIGINVLSAQ TLHTAFARSF
     LLATPLNIYS ALMLTDDLSE GKSFYMKEVD TIKEMISRNQ KGTANLFLFD EIFKGTNTTE
     RIAAAKAVLS YLNTHDNIIV ASTHDTELAT LLDKEYDLYH FSEVIEGETF FFDYKLKNGP
     LYQRNAIRLL EINGFPPIVI RDAYQTIEGM TKQ
//