ID   K5ZIN1_9BACT            Unreviewed;       257 AA.
AC   K5ZIN1;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   24-JAN-2024, entry version 32.
DE   RecName: Full=Tetrapyrrole biosynthesis uroporphyrinogen III synthase domain-containing protein {ECO:0000259|Pfam:PF02602};
GN   ORFNames=HMPREF1077_01559 {ECO:0000313|EMBL:EKN11301.1};
OS   Parabacteroides johnsonii CL02T12C29.
OC   Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Tannerellaceae;
OC   Parabacteroides.
OX   NCBI_TaxID=999419 {ECO:0000313|EMBL:EKN11301.1, ECO:0000313|Proteomes:UP000001218};
RN   [1] {ECO:0000313|EMBL:EKN11301.1, ECO:0000313|Proteomes:UP000001218}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CL02T12C29 {ECO:0000313|EMBL:EKN11301.1,
RC   ECO:0000313|Proteomes:UP000001218};
RG   The Broad Institute Genome Sequencing Platform;
RA   Earl A., Ward D., Feldgarden M., Gevers D., Zitomersky N.L., Coyne M.J.,
RA   Comstock L.E., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA   Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA   Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Parabacteroides johnsonii CL02T12C29.";
RL   Submitted (FEB-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKN11301.1}.
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DR   EMBL; AGZP01000015; EKN11301.1; -; Genomic_DNA.
DR   AlphaFoldDB; K5ZIN1; -.
DR   PATRIC; fig|999419.3.peg.1597; -.
DR   eggNOG; COG1587; Bacteria.
DR   HOGENOM; CLU_076006_0_0_10; -.
DR   OrthoDB; 1149788at2; -.
DR   Proteomes; UP000001218; Unassembled WGS sequence.
DR   GO; GO:0004852; F:uroporphyrinogen-III synthase activity; IEA:InterPro.
DR   GO; GO:0006780; P:uroporphyrinogen III biosynthetic process; IEA:InterPro.
DR   CDD; cd06578; HemD; 1.
DR   Gene3D; 3.40.50.10090; -; 2.
DR   InterPro; IPR036108; 4pyrrol_syn_uPrphyn_synt_sf.
DR   InterPro; IPR003754; 4pyrrol_synth_uPrphyn_synth.
DR   InterPro; IPR039793; UROS/Hem4.
DR   PANTHER; PTHR12390; UROPORPHYRINOGEN III SYNTHASE; 1.
DR   PANTHER; PTHR12390:SF0; UROPORPHYRINOGEN-III SYNTHASE; 1.
DR   Pfam; PF02602; HEM4; 1.
DR   SUPFAM; SSF69618; HemD-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001218}.
FT   DOMAIN          26..238
FT                   /note="Tetrapyrrole biosynthesis uroporphyrinogen III
FT                   synthase"
FT                   /evidence="ECO:0000259|Pfam:PF02602"
SQ   SEQUENCE   257 AA;  29275 MW;  4E2F397B5C79CCAD CRC64;
     MALNIKKLLV SQPKPASEKS PYFDIAEKYG VEIDFRPFIK VEPLSSKEFR QQKISILDHT
     AVVFTARTAI DHFFHLCEEL RVAIPETMKY FCMTEAIAVY LQKYIVYRKR KIFFGQTGKL
     DDLVTVIGKH AKEKYLVPVS DVHKDDLLTM LEAKKISFTK AVMYRTVSND FSKDEKFDYD
     MLVFFSPSGI SSLLKNFPNF KQEDIKIGCF GPTTAKAVKE AGLRLDVEAP TPEAPSMTAA
     LELYLKKEMG SNKKNGK
//