ID   K6GG75_9GAMM            Unreviewed;       280 AA.
AC   K6GG75;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   03-MAY-2023, entry version 30.
DE   SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:EKO36031.1};
GN   ORFNames=B273_0645 {ECO:0000313|EMBL:EKO36031.1};
OS   SAR86 cluster bacterium SAR86E.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; SAR86 cluster.
OX   NCBI_TaxID=1208365 {ECO:0000313|EMBL:EKO36031.1, ECO:0000313|Proteomes:UP000010310};
RN   [1] {ECO:0000313|EMBL:EKO36031.1, ECO:0000313|Proteomes:UP000010310}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SAR86E {ECO:0000313|EMBL:EKO36031.1};
RA   Dupont C.L., Rusch D.B., Lombardo M.-J., Novotny M., Yee-Greenbaum J.,
RA   Laskin R.;
RL   Submitted (SEP-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EKO36031.1}.
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DR   EMBL; AMWX01000012; EKO36031.1; -; Genomic_DNA.
DR   AlphaFoldDB; K6GG75; -.
DR   STRING; 1208365.B273_0645; -.
DR   Proteomes; UP000010310; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR   GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR   Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR046825; PDH_C.
DR   InterPro; IPR046826; PDH_N.
DR   InterPro; IPR003099; Prephen_DH.
DR   PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR   PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR   Pfam; PF20463; PDH_C; 1.
DR   Pfam; PF02153; PDH_N; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS51176; PDH_ADH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010310}.
FT   DOMAIN          1..280
FT                   /note="Prephenate/arogenate dehydrogenase"
FT                   /evidence="ECO:0000259|PROSITE:PS51176"
SQ   SEQUENCE   280 AA;  30874 MW;  402EE2F9FAB53B6A CRC64;
     MKIIIIGLGL IGGSIAKTLS NSEDFEILAF DSDQSSIKNA LDKKSIQGSL HSLDDLVNPE
     YENSLVIITT PPSATNRILR SLEFLFNSSI TITDTTSTKS FLKKTLQEFS FPKNFIFSHP
     VAGSHLSGEK NSVADLFNGK STILSYHDLV ESKHVDRVTN LWNILGSKIT VLDADLHDQI
     FAYSSHLPHV AAYALLNTLK GLEQDDLSDF SGGGLGEFLR LASSSPEMWA DIFSMNETNI
     SIAIDDLIKS LEILKDKIGK DPNSLKTFLV ELKNFKESNF
//