ID K6TX16_9CLOT Unreviewed; 311 AA.
AC K6TX16;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=DMT(Drug/metabolite transporter) superfamily permease {ECO:0000313|EMBL:EKQ51587.1};
GN ORFNames=A370_04765 {ECO:0000313|EMBL:EKQ51587.1};
OS Clostridium sp. Maddingley MBC34-26.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1196322 {ECO:0000313|EMBL:EKQ51587.1, ECO:0000313|Proteomes:UP000001325};
RN [1] {ECO:0000313|EMBL:EKQ51587.1, ECO:0000313|Proteomes:UP000001325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34-26 {ECO:0000313|Proteomes:UP000001325};
RX PubMed=23405323;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Bradbury M.I.,
RA Midgley D.J., Hendry P.;
RT "Draft Genome Sequence of Clostridium sp. Maddingley, Isolated from Coal-
RT Seam Gas Formation Water.";
RL Genome Announc. 1:E00081-12(2013).
CC -!- SIMILARITY: Belongs to the EamA transporter family.
CC {ECO:0000256|ARBA:ARBA00007362}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ51587.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ALXI01000155; EKQ51587.1; -; Genomic_DNA.
DR AlphaFoldDB; K6TX16; -.
DR STRING; 1196322.A370_04765; -.
DR PATRIC; fig|1196322.3.peg.4630; -.
DR eggNOG; COG0697; Bacteria.
DR Proteomes; UP000001325; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR000620; EamA_dom.
DR PANTHER; PTHR32322; INNER MEMBRANE TRANSPORTER; 1.
DR PANTHER; PTHR32322:SF2; PROTEIN PAGO; 1.
DR Pfam; PF00892; EamA; 2.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001325};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 39..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 68..84
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 96..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 188..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..267
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 9..140
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
FT DOMAIN 152..288
FT /note="EamA"
FT /evidence="ECO:0000259|Pfam:PF00892"
SQ SEQUENCE 311 AA; 35178 MW; 4C31A712E607523A CRC64;
MTNKKNIAGH LSALITIMVW GTTFVSTKVL LKDFLPIEIL FFRFIIGYFT LFLAYPHKLK
NLNFKQELYF AAAGLFGITL YFLFENIALT YTLASNVGVI VSIAPFFTAL VAHMFLDSEK
LSLRFFVGFI VAILGIILIG FNENFVLKLN PLGDILAVLA TIVWAFYSVI MRKISEFGYN
TLGCTRRVFF YGLLFMIPAI YMFDFKLQLN RFTIPSNLFN ILYLGFGASA ICFATWNWSV
KILGAVKTSV YIYIVPVITV VASAFLLHEN ITSIATIGIF LALAGLLISE EKPIMILMGK
IDQLRVKYRM R
//
