ID K6TYL4_9CLOT Unreviewed; 667 AA.
AC K6TYL4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Methyl-accepting chemotaxis protein {ECO:0000313|EMBL:EKQ52247.1};
GN ORFNames=A370_04408 {ECO:0000313|EMBL:EKQ52247.1};
OS Clostridium sp. Maddingley MBC34-26.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1196322 {ECO:0000313|EMBL:EKQ52247.1, ECO:0000313|Proteomes:UP000001325};
RN [1] {ECO:0000313|EMBL:EKQ52247.1, ECO:0000313|Proteomes:UP000001325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34-26 {ECO:0000313|Proteomes:UP000001325};
RX PubMed=23405323;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Bradbury M.I.,
RA Midgley D.J., Hendry P.;
RT "Draft Genome Sequence of Clostridium sp. Maddingley, Isolated from Coal-
RT Seam Gas Formation Water.";
RL Genome Announc. 1:E00081-12(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the methyl-accepting chemotaxis (MCP) protein
CC family. {ECO:0000256|ARBA:ARBA00029447}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ52247.1}.
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DR EMBL; ALXI01000140; EKQ52247.1; -; Genomic_DNA.
DR AlphaFoldDB; K6TYL4; -.
DR STRING; 1196322.A370_04408; -.
DR PATRIC; fig|1196322.3.peg.4300; -.
DR eggNOG; COG0840; Bacteria.
DR Proteomes; UP000001325; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:UniProtKB-KW.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd11386; MCP_signal; 1.
DR CDD; cd12913; PDC1_MCP_like; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 1.10.8.500; HAMP domain in histidine kinase; 1.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR004089; MCPsignal_dom.
DR InterPro; IPR029151; Sensor-like_sf.
DR PANTHER; PTHR32089:SF92; LYSOZYME-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR32089; METHYL-ACCEPTING CHEMOTAXIS PROTEIN MCPB; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF00015; MCPsignal; 1.
DR SMART; SM00304; HAMP; 2.
DR SMART; SM00283; MA; 1.
DR SUPFAM; SSF58104; Methyl-accepting chemotaxis protein (MCP) signaling domain; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 1.
DR PROSITE; PS50111; CHEMOTAXIS_TRANSDUC_2; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Chemotaxis {ECO:0000256|ARBA:ARBA00022500};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001325};
KW Transducer {ECO:0000256|ARBA:ARBA00023224, ECO:0000256|PROSITE-
KW ProRule:PRU00284};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 15..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 309..361
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 380..637
FT /note="Methyl-accepting transducer"
FT /evidence="ECO:0000259|PROSITE:PS50111"
FT REGION 399..419
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 667 AA; 73182 MW; 08F94EBB78DAF305 CRC64;
MKSKKFKFNS IRTKLIISLV GICVIPLIIL GYGAYWQANS ILNEKLKVTS QQTLSEVNDG
IDNYFNGFSN TVKMLSTNYN FVNAENSEPY SYIPGLLQNV KESNNDAFSV YFGTADGRFQ
IYPNDKMPDG YNPTERPWYK QALEHKGQVI VTLPFKDSQT GKNTVSIART VEKDNKVVGV
CAMNISIDTL TEKIASKKIG ATGYVFASDV DGKYMIAHPS KDLLGTDAAS KQSFWDKAKS
SDSGFVTYEY NNVKKFGAYA TNNVTGWKLV ATLDEKEISN DTNSILVTML IIVSVIFLIS
IALSLILSKG IAKNIKNLKG VFGKASSGDL TVSIVPSTRD EFMDLAYSFN EMIQNIAELM
NNVTKSSKIV LETSSNLASM SEEVTASVAE VAKAIEEVSE GATNQSQNAQ NGVSEMNELS
SKLDKISTNS NEMDRLSIST KELGAKGLSM VDTLIEKSHK TKIATTEVND IVADMNESTK
KINTISETIS EITEQTNLLA LNASIESARA GEAGKGFAVV AEEIRKLAEE SKASTEEIKA
IITNIQKKSD TAVKAIKSTE YVVNEQDLAV DQTQEIFKEI LKAIETMINK VEEIKLSITD
VNEKKQSAVS EIENISSISQ ETASASEEVT ASTEEITAVM DRFTKYADEL QVLAEKLDSE
LEKFKIN
//
