ID K6U473_9CLOT Unreviewed; 268 AA.
AC K6U473;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE SubName: Full=Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC {ECO:0000313|EMBL:EKQ55487.1};
GN ORFNames=A370_02703 {ECO:0000313|EMBL:EKQ55487.1};
OS Clostridium sp. Maddingley MBC34-26.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1196322 {ECO:0000313|EMBL:EKQ55487.1, ECO:0000313|Proteomes:UP000001325};
RN [1] {ECO:0000313|EMBL:EKQ55487.1, ECO:0000313|Proteomes:UP000001325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34-26 {ECO:0000313|Proteomes:UP000001325};
RX PubMed=23405323;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Bradbury M.I.,
RA Midgley D.J., Hendry P.;
RT "Draft Genome Sequence of Clostridium sp. Maddingley, Isolated from Coal-
RT Seam Gas Formation Water.";
RL Genome Announc. 1:E00081-12(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ55487.1}.
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DR EMBL; ALXI01000094; EKQ55487.1; -; Genomic_DNA.
DR AlphaFoldDB; K6U473; -.
DR STRING; 1196322.A370_02703; -.
DR PATRIC; fig|1196322.3.peg.2619; -.
DR eggNOG; COG3715; Bacteria.
DR Proteomes; UP000001325; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0009401; P:phosphoenolpyruvate-dependent sugar phosphotransferase system; IEA:InterPro.
DR InterPro; IPR004700; PTS_IIC_man.
DR PANTHER; PTHR32502; N-ACETYLGALACTOSAMINE PERMEASE II COMPONENT-RELATED; 1.
DR PANTHER; PTHR32502:SF25; PHOSPHOTRANSFERASE SYSTEM, MANNOSE-SPECIFIC EIIC; 1.
DR Pfam; PF03609; EII-Sor; 1.
DR PROSITE; PS51106; PTS_EIIC_TYPE_4; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001325};
KW Transferase {ECO:0000313|EMBL:EKQ55487.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 32..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 66..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 93..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 141..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 247..268
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 268 AA; 26875 MW; DF35A66BE4C154FB CRC64;
MTLNIVQVIL VILIAFLAGV EGILDEFQFH QPIIACTLIG LVTGNLLPCL ILGGTLQMIA
LGWANIGAAV APDAALAAVA SAIILVLGGQ GEAGVASAIA IAVPLAVAGL LLTIICRTIA
TAFVHFMDAA AKEGNIRAIE MWQIAAICLQ GVRIAIPAGL VLAIGAGPIG ALLAAMPAWL
TGGLAIGGGM VVAVGYAMVI NMMATKEVWP FFAIGFVLAT VSQITLIGLG AIGVAIALAY
LALSKQGGSG NGGSSNTGDP LGDLIDRY
//
