ID K6U5G5_9CLOT Unreviewed; 392 AA.
AC K6U5G5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Site-specific recombinase XerD {ECO:0000313|EMBL:EKQ56202.1};
GN ORFNames=A370_02179 {ECO:0000313|EMBL:EKQ56202.1};
OS Clostridium sp. Maddingley MBC34-26.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1196322 {ECO:0000313|EMBL:EKQ56202.1, ECO:0000313|Proteomes:UP000001325};
RN [1] {ECO:0000313|EMBL:EKQ56202.1, ECO:0000313|Proteomes:UP000001325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34-26 {ECO:0000313|Proteomes:UP000001325};
RX PubMed=23405323;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Bradbury M.I.,
RA Midgley D.J., Hendry P.;
RT "Draft Genome Sequence of Clostridium sp. Maddingley, Isolated from Coal-
RT Seam Gas Formation Water.";
RL Genome Announc. 1:E00081-12(2013).
CC -!- FUNCTION: Site-specific tyrosine recombinase, which acts by catalyzing
CC the cutting and rejoining of the recombining DNA molecules.
CC {ECO:0000256|ARBA:ARBA00003283}.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ56202.1}.
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DR EMBL; ALXI01000078; EKQ56202.1; -; Genomic_DNA.
DR AlphaFoldDB; K6U5G5; -.
DR STRING; 1196322.A370_02179; -.
DR PATRIC; fig|1196322.3.peg.2116; -.
DR eggNOG; COG0582; Bacteria.
DR Proteomes; UP000001325; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR CDD; cd01189; INT_ICEBs1_C_like; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR028259; AP2-like_int_N.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30349; PHAGE INTEGRASE-RELATED; 1.
DR PANTHER; PTHR30349:SF89; PROPHAGE INTEGRASE INTE; 1.
DR Pfam; PF14657; Arm-DNA-bind_4; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000001325}.
FT DOMAIN 176..385
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 392 AA; 45438 MW; F05B0FE122417D3C CRC64;
MAKRSNGDGS SGWVTKNGRK YWSIAVSVGY DPLTGKLKRK YIYGKTQKEA KAKLKEFEEN
YVENSDNSTL GNFYYDWLWN IKRPSLKDST FEKWEGIYRN YIKPNKGLND AKLTDIDTLA
LQKITTALLK KHTLSQVKTM NSCLGNCFRY AKSINKIKYN PVEGLIYPKN HNVVEEKENY
ISEDDQKRFI SALEGDPLEG IILMGLMCGV RLGEAMALQV KDFDFNHMNV KIKKSVKYVW
TGERDKEGKK IYANKVTIPK TRTSIREVPL PGMLKPIIKG LIKKNMEHKL KYGELYIDNS
LIFCKENGDY IDNKKPNRHL KIALKKAGIK SDIHYHSLRH IFITNCLSRD INPRTVMDWV
GHTDIKMTML VYAEINKDKN KKEYEKINCM FD
//
