ID K6U867_9CLOT Unreviewed; 576 AA.
AC K6U867;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE SubName: Full=Ubiquitin-protein ligase {ECO:0000313|EMBL:EKQ57912.1};
GN ORFNames=A370_00419 {ECO:0000313|EMBL:EKQ57912.1};
OS Clostridium sp. Maddingley MBC34-26.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=1196322 {ECO:0000313|EMBL:EKQ57912.1, ECO:0000313|Proteomes:UP000001325};
RN [1] {ECO:0000313|EMBL:EKQ57912.1, ECO:0000313|Proteomes:UP000001325}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Maddingley MBC34-26 {ECO:0000313|Proteomes:UP000001325};
RX PubMed=23405323;
RA Rosewarne C.P., Greenfield P., Li D., Tran-Dinh N., Bradbury M.I.,
RA Midgley D.J., Hendry P.;
RT "Draft Genome Sequence of Clostridium sp. Maddingley, Isolated from Coal-
RT Seam Gas Formation Water.";
RL Genome Announc. 1:E00081-12(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKQ57912.1}.
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DR EMBL; ALXI01000009; EKQ57912.1; -; Genomic_DNA.
DR AlphaFoldDB; K6U867; -.
DR STRING; 1196322.A370_00419; -.
DR PATRIC; fig|1196322.3.peg.411; -.
DR eggNOG; COG1716; Bacteria.
DR eggNOG; COG5078; Bacteria.
DR Proteomes; UP000001325; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR CDD; cd00060; FHA; 1.
DR Gene3D; 2.60.200.20; -; 1.
DR Gene3D; 3.10.110.10; Ubiquitin Conjugating Enzyme; 1.
DR InterPro; IPR000253; FHA_dom.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR000608; UBQ-conjugat_E2.
DR InterPro; IPR016135; UBQ-conjugating_enzyme/RWD.
DR Pfam; PF00498; FHA; 1.
DR Pfam; PF00179; UQ_con; 1.
DR SMART; SM00240; FHA; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF54495; UBC-like; 1.
DR PROSITE; PS50006; FHA_DOMAIN; 1.
PE 4: Predicted;
KW Ligase {ECO:0000313|EMBL:EKQ57912.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001325};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 254..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 322..342
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 503..553
FT /note="FHA"
FT /evidence="ECO:0000259|PROSITE:PS50006"
SQ SEQUENCE 576 AA; 62308 MW; CBBEFF11EF2C5B1C CRC64;
MNARLRRIAA DYEDIKKHFD GHKYIIVEPI GPEPAEKYKI TYYINGIYMI EEGKVETLNK
HIVIITLHSE YPRYKPLCTI ETPIWHPNFK DGQICIGDIW GAGESLSDII VNIGDMIQYK
SWNSYSPLSA AAAKWAIANK HLFPIGNIDL WTGEEVSGII PSNFDIDIFD EEGGAIKGDE
SIETIDPLPI EEEIVESESS LIAATTTEKI EEENDFDITA DELEGIEFIP TTARMQSSQQ
AVVPKGGKIN FKTIFMKGIL YGLIGGFIAW GIAEIAPIHT KTILAWRGHP YDSLMSEVIS
GKISQTQFYA LIGSATLMES SLFSAIIGGL IGAVMGIGEG IYYGSKEKAV KYGLIGLGIA
LLIGLVGGFL AQLLYSSLLS GVNEYTSEIY LAFVRAIGWS VMGAGVGVAI GLIKPEKMRV
INCVLGGIVG GFIGGFLFNF IANSVNASGG NSGVIPRAIG IIIMGALVGL GIGLLEQFAK
SAWLKVIRGE FEGKEYLVFQ GITSIGNSGK NTIVLFKDKL VAPKHCEIVQ EGNKYVLVDK
GTPSGTLVNG IRIGRHVLKQ GDAISLGNSV LVFNTK
//
