ID K6W2U5_9ACTN Unreviewed; 515 AA.
AC K6W2U5;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Putative sodium/amino acid symporter {ECO:0000313|EMBL:GAB93485.1};
GN ORFNames=GORHZ_225_00080 {ECO:0000313|EMBL:GAB93485.1};
OS Gordonia rhizosphera NBRC 16068.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1108045 {ECO:0000313|EMBL:GAB93485.1, ECO:0000313|Proteomes:UP000008363};
RN [1] {ECO:0000313|EMBL:GAB93485.1, ECO:0000313|Proteomes:UP000008363}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 16068 {ECO:0000313|EMBL:GAB93485.1,
RC ECO:0000313|Proteomes:UP000008363};
RA Takarada H., Isaki S., Hosoyama A., Tsuchikane K., Katsumata H., Baba S.,
RA Ohji S., Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia rhizosphera NBRC 16068.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAB93485.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BAHC01000225; GAB93485.1; -; Genomic_DNA.
DR RefSeq; WP_006338752.1; NZ_BAHC01000225.1.
DR AlphaFoldDB; K6W2U5; -.
DR STRING; 1108045.GORHZ_225_00080; -.
DR eggNOG; COG1115; Bacteria.
DR OrthoDB; 9806926at2; -.
DR Proteomes; UP000008363; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF7; SODIUM_PROTON-DEPENDENT ALANINE CARRIER PROTEIN YRBD-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
DR PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363064};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Reference proteome {ECO:0000313|Proteomes:UP000008363};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 12..30
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 145..166
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 186..204
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 243..267
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 302..325
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 370..390
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 411..434
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 446..470
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 515 AA; 54674 MW; 46B5D17C6E550806 CRC64;
MSDFLSDVNG YIWSNALVFL CLAAGVFFSI RTRLVQVRMF VEMIRLMFKG ERSPSGVSSF
QALSISLAGR VGTGNIAGVA TAIAFGGPGA LFWMWVVAFL GASTSYVECT LGQIYKGHDP
ITGEYRGGPA YYFSRAFAHT KAAPFFRVYG LIFAAVTVLA CGLLLPSVQS NSMAVALNNA
WGLSEWVVAV ASVIVLAFVI IGGVKRIANF ASIVVPFMAI VYIGLALIIV VTNASAVPEV
FRVVFSSAFG IDSAFGAIIG TAIMWGVKRG IYSNEAGQGT GPHAAAAAEV SHPTKQGLVQ
AFAVYIDTLF VCSATGFLIL STGAYRVFEG ESSSGAILAD GGALPADVEV GPTFVQTGFD
TLWSGAGSSF VAISLLFFCL TTIIAYYYMA ETNLRFLMGK SATLYIKPLR STLGSNITML
LQTLILVSVV IGAVSTATDA WTLGDIGVGL MAWLNIVGII ILQQPAFAAL RDYERQKKQG
IDPIFDPIAL GIPNATFWEL RDPKTGKERE PVGSV
//
