GenomeNet

Database: UniProt
Entry: K6W7A1_9MICO
LinkDB: K6W7A1_9MICO
Original site: K6W7A1_9MICO 
ID   K6W7A1_9MICO            Unreviewed;       556 AA.
AC   K6W7A1;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   31-JUL-2019, entry version 30.
DE   RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423};
DE            EC=2.3.1.- {ECO:0000256|RuleBase:RU003423};
GN   ORFNames=KILIM_016_00100 {ECO:0000313|EMBL:GAB95070.1};
OS   Kineosphaera limosa NBRC 100340.
OC   Bacteria; Actinobacteria; Micrococcales; Dermatophilaceae;
OC   Kineosphaera.
OX   NCBI_TaxID=1184609 {ECO:0000313|EMBL:GAB95070.1, ECO:0000313|Proteomes:UP000008366};
RN   [1] {ECO:0000313|EMBL:GAB95070.1, ECO:0000313|Proteomes:UP000008366}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBRC 100340 {ECO:0000313|EMBL:GAB95070.1,
RC   ECO:0000313|Proteomes:UP000008366};
RA   Yoshida I., Isaki S., Hosoyama A., Tsuchikane K., Katsumata H.,
RA   Ando Y., Ohji S., Hamada M., Tamura T., Yamazoe A., Yamazaki S.,
RA   Fujita N.;
RT   "Whole genome shotgun sequence of Kineosphaera limosa NBRC 100340.";
RL   Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|RuleBase:RU003423};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003423}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:GAB95070.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; BAHD01000016; GAB95070.1; -; Genomic_DNA.
DR   STRING; 1184609.KILIM_016_00100; -.
DR   EnsemblBacteria; GAB95070; GAB95070; KILIM_016_00100.
DR   Proteomes; UP000008366; Unassembled WGS sequence.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.559.10; -; 1.
DR   Gene3D; 4.10.320.10; -; 1.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR014276; 2-oxoglutarate_DH_E2.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 2.
DR   Pfam; PF02817; E3_binding; 1.
DR   SUPFAM; SSF47005; SSF47005; 1.
DR   SUPFAM; SSF51230; SSF51230; 2.
DR   TIGRFAMs; TIGR02927; SucB_Actino; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 2.
DR   PROSITE; PS00189; LIPOYL; 2.
DR   PROSITE; PS51826; PSBD; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003423,
KW   ECO:0000313|EMBL:GAB95070.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008366};
KW   Lipoyl {ECO:0000256|RuleBase:RU003423, ECO:0000256|SAAS:SAAS00065550};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008366};
KW   Transferase {ECO:0000256|RuleBase:RU003423,
KW   ECO:0000313|EMBL:GAB95070.1}.
FT   DOMAIN        1     64       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
FT   DOMAIN      113    188       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
FT   DOMAIN      239    276       Peripheral subunit-binding (PSBD).
FT                                {ECO:0000259|PROSITE:PS51826}.
FT   REGION       51    160       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      183    237       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      275    330       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     65     93       Acidic. {ECO:0000256|SAM:MobiDB-lite}.
FT   COMPBIAS    203    235       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
SQ   SEQUENCE   556 AA;  57988 MW;  EA94219B3E48C3A9 CRC64;
     MTEGTVTRWL KSVGEEVAAD EPLLEVSTDK VDTEVPSPVA GTLQKILVDE DETAEVGADL
     CIIGDGPADD DDDSGDDSAK DEEPQEEASA DDSSDEPQEK PKKSSGGGGV SGGEKVQMPA
     LGESVTEGTV TRWLKEEGDD VEVDEPLLEV STDKVDTEVP SPVAGKLTKI LVAEDETAEV
     GADLCIIGGE ASDDGDDDEP EAESTPEPKK EEPKPAAKEQ PAKDDSAKDD SGKDDASAYV
     TPLVRKLAAD HGVDLGSLKG TGVGGRIRKQ DVLDAAKAKE EPEPEQQAAP APSDSAPAPV
     AAAPAPSGGP AKATKVPEPD TTKRGTTEKL SRLRKIVAQR MVESLQTSAQ LTAVVEVDMS
     RVAALRARNK NEFKAREGAN LSFLPFICLA TVEALKAFPA LNSSIDGESV VYHGAEHLAI
     AVDTPRGLVV PVIKDAGDLN IAGLARKIAD VAARTRSNKI GPDELSGGTF TISNIGSAGT
     VSDTPIINQP QVGILGTGTI VKRPVVVTDA DGNEAIGIRS MMNLCLTYDH RIVDGADAGR
     FLSALKSRLE EGAFEL
//
DBGET integrated database retrieval system