ID K6X652_9ACTN Unreviewed; 313 AA.
AC K6X652;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012415};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415};
GN Name=galU {ECO:0000313|EMBL:GAC01567.1};
GN ORFNames=GONAM_29_00110 {ECO:0000313|EMBL:GAC01567.1};
OS Gordonia namibiensis NBRC 108229.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1208314 {ECO:0000313|EMBL:GAC01567.1, ECO:0000313|Proteomes:UP000035058};
RN [1] {ECO:0000313|EMBL:GAC01567.1, ECO:0000313|Proteomes:UP000035058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 108229 {ECO:0000313|EMBL:GAC01567.1,
RC ECO:0000313|Proteomes:UP000035058};
RA Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Katsumata H., Baba S.,
RA Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia namibiensis NBRC 108229.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC01567.1}.
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DR EMBL; BAHE01000029; GAC01567.1; -; Genomic_DNA.
DR RefSeq; WP_006867733.1; NZ_BAHE01000029.1.
DR AlphaFoldDB; K6X652; -.
DR Proteomes; UP000035058; Unassembled WGS sequence.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF1; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000313|EMBL:GAC01567.1};
KW Transferase {ECO:0000313|EMBL:GAC01567.1}.
FT DOMAIN 24..290
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 313 AA; 33585 MW; 3DDA410AF0B78357 CRC64;
MTASKDGFSE YESVPNTPPI PRTAVVPAAG LGTRFLPATK TVPKELLPVV DTPGIELVAE
EAKSAGADRL LIVTSPGKDG VVAHFVKDLV LENTLAKRGK EAMLAKVRKA PNLLEVASVV
QEKPLGLGHA VGCVEDRLDD DEDAIAVLLP DDLVLPGGVL EVMARTRQRR GGSVLCAIEV
PEDRISAYGV FDVEPLPDAN NPNVMKLKGM VEKPEPQDAP SNLAAAGRYI LDRKIFDALR
RIKPGAGGEL QLTDAIALLI EEGEPVHVVV HRGTRHDLGN PGGYLKAAVD FALDRDDYGP
DLREWLEKRL AES
//
