ID K6X692_9ACTN Unreviewed; 655 AA.
AC K6X692;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Putative acetoacetyl-CoA synthetase {ECO:0000313|EMBL:GAC01612.1};
GN ORFNames=GONAM_30_00210 {ECO:0000313|EMBL:GAC01612.1};
OS Gordonia namibiensis NBRC 108229.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Gordoniaceae;
OC Gordonia.
OX NCBI_TaxID=1208314 {ECO:0000313|EMBL:GAC01612.1, ECO:0000313|Proteomes:UP000035058};
RN [1] {ECO:0000313|EMBL:GAC01612.1, ECO:0000313|Proteomes:UP000035058}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NBRC 108229 {ECO:0000313|EMBL:GAC01612.1,
RC ECO:0000313|Proteomes:UP000035058};
RA Isaki-Nakamura S., Hosoyama A., Tsuchikane K., Katsumata H., Baba S.,
RA Yamazaki S., Fujita N.;
RT "Whole genome shotgun sequence of Gordonia namibiensis NBRC 108229.";
RL Submitted (AUG-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC01612.1}.
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DR EMBL; BAHE01000030; GAC01612.1; -; Genomic_DNA.
DR RefSeq; WP_006867777.1; NZ_BAHE01000030.1.
DR AlphaFoldDB; K6X692; -.
DR Proteomes; UP000035058; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 24..83
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 99..462
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 539..614
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 655 AA; 70007 MW; 5CFD2F40D980791E CRC64;
MTGAAIERFS RHVENRFGVD AADYDRLWSW SVEQPAQFWR ALWEFFDLDA LAAEPLAEGD
AAVLADPTMP GAQWFPGVRL NYVSQILRHA DLPGAAIVGL DEAGERTEIA WSDLPGMVAS
LAATLRAQGI GTGDVVAAYL PDIPEAVVAF LATAGLGAIW SGCGQDYAPQ GAASRLGQLR
PKVLFSAAGY RYSGKDIDKR ADSAELASLL PELVAHITIG GDAGEPTGDG TTRIDYADAL
TAEAGDAGPV LVDFDHPLWV LFSSGTTGRP KGIVHGHGGV VVEHLKAGAL HGDLSSDDVF
FWQTALSWMM WNYQVAGLLC GARIVCYSGS PLHPDADKLW QIVADEKVTY FGTSPGQLQA
SRKAGLEPGR DHDLSALRAL GSTGSSLAAD LFTWVDDHVK RGLPISSISG GTDIVSAFAG
GSVGVPVVPG ELSVRYLGVA LESWAPDGTP LVGEVGELVV TAPMPSMPVH FWDDPDGARY
RAAYFDHEWE GPTAHPDGPV WRHGDWVTVT ERGSLVIHGR SDATLNRHGI RMGSADIYEV
VESLDEIAEA FVLGVDGPDG AYWMPLFVTL VPGAVLDDAL IARIAAAVRD RLSKRHVPDE
VIEAPGIPHT RTGKKLEVPV TAILAGRSEV NIDPKSVDDY SLVDWYAEQG RAHRW
//
