ID K6XN89_9ALTE Unreviewed; 740 AA.
AC K6XN89;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=LPS-assembly protein LptD {ECO:0000256|HAMAP-Rule:MF_01411};
DE Flags: Precursor;
GN Name=lptD {ECO:0000256|HAMAP-Rule:MF_01411,
GN ECO:0000313|EMBL:GAC13156.1};
GN ORFNames=GLIP_0510 {ECO:0000313|EMBL:GAC13156.1};
OS Aliiglaciecola lipolytica E3.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Aliiglaciecola.
OX NCBI_TaxID=1127673 {ECO:0000313|EMBL:GAC13156.1, ECO:0000313|Proteomes:UP000006334};
RN [1] {ECO:0000313|EMBL:GAC13156.1, ECO:0000313|Proteomes:UP000006334}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E3 {ECO:0000313|EMBL:GAC13156.1,
RC ECO:0000313|Proteomes:UP000006334};
RX PubMed=25009843;
RA Qin Q.-L., Xie B.-B., Yu Y., Shu Y.-L., Rong J.-C., Zhang Y.-J.,
RA Zhao D.-L., Chen X.-L., Zhang X.-Y., Chen B., Zhou B.-C., Zhang Y.-Z.;
RT "Comparative genomics of the marine bacterial genus Glaciecola reveals the
RT high degree of genomic diversity and genomic characteristic for cold
RT adaptation.";
RL Environ. Microbiol. 16:1642-1653(2014).
CC -!- FUNCTION: Together with LptE, is involved in the assembly of
CC lipopolysaccharide (LPS) at the surface of the outer membrane.
CC {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- SUBUNIT: Component of the lipopolysaccharide transport and assembly
CC complex. Interacts with LptE and LptA. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- SIMILARITY: Belongs to the LptD family. {ECO:0000256|HAMAP-
CC Rule:MF_01411}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|HAMAP-Rule:MF_01411}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC13156.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BAEN01000015; GAC13156.1; -; Genomic_DNA.
DR RefSeq; WP_008842976.1; NZ_BAEN01000015.1.
DR AlphaFoldDB; K6XN89; -.
DR STRING; 1127673.GLIP_0510; -.
DR eggNOG; COG1452; Bacteria.
DR OrthoDB; 9760225at2; -.
DR Proteomes; UP000006334; Unassembled WGS sequence.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043165; P:Gram-negative-bacterium-type cell outer membrane assembly; IEA:UniProtKB-UniRule.
DR GO; GO:0015920; P:lipopolysaccharide transport; IEA:InterPro.
DR GO; GO:0010033; P:response to organic substance; IEA:InterPro.
DR HAMAP; MF_01411; LPS_assembly_LptD; 1.
DR InterPro; IPR020889; LipoPS_assembly_LptD.
DR InterPro; IPR007543; LptD_C.
DR InterPro; IPR005653; OstA-like_N.
DR PANTHER; PTHR30189; LPS-ASSEMBLY PROTEIN; 1.
DR PANTHER; PTHR30189:SF1; LPS-ASSEMBLY PROTEIN LPTD; 1.
DR Pfam; PF04453; LptD; 1.
DR Pfam; PF03968; LptD_N; 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237, ECO:0000256|HAMAP-
KW Rule:MF_01411};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|HAMAP-Rule:MF_01411};
KW Reference proteome {ECO:0000313|Proteomes:UP000006334};
KW Signal {ECO:0000256|HAMAP-Rule:MF_01411}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT CHAIN 23..740
FT /note="LPS-assembly protein LptD"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_01411"
FT /id="PRO_5009016176"
FT DOMAIN 48..175
FT /note="Organic solvent tolerance-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF03968"
FT DOMAIN 287..647
FT /note="LptD C-terminal"
FT /evidence="ECO:0000259|Pfam:PF04453"
SQ SEQUENCE 740 AA; 84708 MW; 9C874A37DE6414A7 CRC64;
MQINQTTSLL FICAFGSVTA QAESLYTCPI NTDNFAADQT ISTDQIRVKA NRAEIKQNRY
ATFEGDITID SESAQILADN ATIDKDKSEL NASGDVSYKD ALMVVQSRDV RLNTESGQLS
MNDTQYRLSQ FGGRGSASAI DIDQQVGLEL TNVSYTTCPE GDEDWKINAS SIKIEEDALW
GEAVNTVFYL QDIPVFYLPY FVFPVSDQRQ TGLLFPEITT SSTTGLSYEQ PFYWNIAENF
DATISPRLMT DSGLMLNTEF RYLTQTSAGQ VNIEYLNNDK SIDDNSSRYF YRLMNVTNVG
DKWNLNIDYN GLSDDNFIVD FGSDYYNRAD THLYQTVALN YYSDDLDFSL SIKDFEIIGD
HPTNYRALPE LKLNYQTDIF AGLEFRINSE LAYFENQQAN LPEATRFHIA PSLALPLRAH
WGEFLAEATL LNTYYRQDNI EGTELEHRTS RSLGQGRIYG ALHFEKDTEW FGNNLQQTLE
PKIQYLYTSF EDQNQIGLYD TTRLLNDFNG LFRGQEFTGL DRISDNNQVT VGLTTRILDE
NSREQFALSL GQIFYLKDNR VVAASKDENK SALASELDWQ IGSKWFAHSE IQVATKTDKV
ERSSISLEYQ LSEDKIFQIN HRFVRNLSGE KIDQFGLTAS WPLAKNWHWV GRWYKDLNSQ
RTIETYTGIQ YESCCWAISL IGQRNLSNRF DDSGMQDTQE FESSINLKFS FKFTGGEART
NRRDMLEDGL FGYRQAYLIN
//
