ID K6ZAG4_9ALTE Unreviewed; 849 AA.
AC K6ZAG4;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN Name=uvrA {ECO:0000313|EMBL:GAC27327.1};
GN ORFNames=GPAL_0447 {ECO:0000313|EMBL:GAC27327.1};
OS Glaciecola pallidula DSM 14239 = ACAM 615.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Glaciecola.
OX NCBI_TaxID=1121922 {ECO:0000313|EMBL:GAC27327.1, ECO:0000313|Proteomes:UP000006251};
RN [1] {ECO:0000313|EMBL:GAC27327.1, ECO:0000313|Proteomes:UP000006251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACAM 615 {ECO:0000313|EMBL:GAC27327.1,
RC ECO:0000313|Proteomes:UP000006251};
RX PubMed=25009843;
RA Qin Q.-L., Xie B.-B., Yu Y., Shu Y.-L., Rong J.-C., Zhang Y.-J.,
RA Zhao D.-L., Chen X.-L., Zhang X.-Y., Chen B., Zhou B.-C., Zhang Y.-Z.;
RT "Comparative genomics of the marine bacterial genus Glaciecola reveals the
RT high degree of genomic diversity and genomic characteristic for cold
RT adaptation.";
RL Environ. Microbiol. 16:1642-1653(2014).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC27327.1}.
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DR EMBL; BAEQ01000009; GAC27327.1; -; Genomic_DNA.
DR RefSeq; WP_006008784.1; NZ_BAEQ01000009.1.
DR AlphaFoldDB; K6ZAG4; -.
DR STRING; 1121922.GCA_000428905_03010; -.
DR OrthoDB; 9809851at2; -.
DR Proteomes; UP000006251; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 491..848
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 849 AA; 93016 MW; 5DD505AD4CA6E650 CRC64;
MTKVSENATS VQMKAKNVAC DPDHCIQVRG ARVHNLKNID VDLPRNALVV FTGISGSGKS
SLAFGTLFAE SQRRFLDSVS PYARRLIDQV DEPDVDTIDG LPPAVALQQQ RGTPSVRSFV
GSVTRISTAL RMLYSRAGKY PRGQNILYAD AFSANTPQGA CNKCHGIGRV FEVTEKLLVP
DDTKTIRERA IAAWPPAWQG QNLSRILVSL GYDIDKPWKT LPKKTRDWIL FTDETPVVPV
YPEYNFARIS EAIEKGEEPH YMGKFSSARR FILQSFATTQ SPRTKKRVSQ FMQISKCPDC
NGKKLKRESL SVKFAGLDIG ELSRLTLTEL ARLLGDAANV NPADSDLHPE KAIVAQRIAR
DILVRVKALT RLGLGYLSLE RSTPTLSPGE LQRLRLATQI HSQLFGVVYV LDEPSAGLHP
ADTQALLGAL DELILAGNSL FVVEHDVSVI RHADWIVDVG PDAGTHGGEV IYSGPIDGLR
KVTKSHTRRF LFTADAAAKP LPRQPTGWLK LAGIERNNLQ GLNVEFPLGV MTTVTGVSGS
GKSSLVSQAL VELVYDALGQ KKTIEVPNSE VELLEREIET STGGRIVDGM QHLRRMVTVD
QKAIGRTPRS NLATYTSLFD HVRKLFASTR KSKVRRYDVG RFSFNVVKGR CSNCEGVGFV
SVELLFLPSV YSPCPVCRGQ RYNDKTLEVT YRGKNIAEVL ELTVESAHDF FENEPPILRA
LDALLQVGLG YLRLGQPATE LSGGEAQRIK LATELQRTQR GDTLYVLDEP TNGLHPADVS
MLMSQLNELV DAGNTVIMVE HDMQAASSSD WVIDIGPGAG DEGGLVVAQG SPAKVAKSKT
SRTAPFLLT
//
