ID K6ZBD3_9ALTE Unreviewed; 415 AA.
AC K6ZBD3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=3-oxoacyl-[acyl-carrier-protein] synthase II {ECO:0000313|EMBL:GAC33406.1};
DE EC=2.3.1.179 {ECO:0000313|EMBL:GAC33406.1};
GN Name=fabF {ECO:0000313|EMBL:GAC33406.1};
GN ORFNames=GPLA_2504 {ECO:0000313|EMBL:GAC33406.1};
OS Paraglaciecola polaris LMG 21857.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Paraglaciecola.
OX NCBI_TaxID=1129793 {ECO:0000313|EMBL:GAC33406.1, ECO:0000313|Proteomes:UP000006322};
RN [1] {ECO:0000313|EMBL:GAC33406.1, ECO:0000313|Proteomes:UP000006322}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 21857 {ECO:0000313|EMBL:GAC33406.1,
RC ECO:0000313|Proteomes:UP000006322};
RX PubMed=25009843;
RA Qin Q.-L., Xie B.-B., Yu Y., Shu Y.-L., Rong J.-C., Zhang Y.-J.,
RA Zhao D.-L., Chen X.-L., Zhang X.-Y., Chen B., Zhou B.-C., Zhang Y.-Z.;
RT "Comparative genomics of the marine bacterial genus Glaciecola reveals the
RT high degree of genomic diversity and genomic characteristic for cold
RT adaptation.";
RL Environ. Microbiol. 16:1642-1653(2014).
CC -!- PATHWAY: Lipid metabolism; fatty acid biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005194}.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP
CC synthases family. {ECO:0000256|ARBA:ARBA00008467,
CC ECO:0000256|RuleBase:RU003694}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC33406.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BAER01000060; GAC33406.1; -; Genomic_DNA.
DR AlphaFoldDB; K6ZBD3; -.
DR STRING; 1129793.GPLA_2504; -.
DR UniPathway; UPA00094; -.
DR Proteomes; UP000006322; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00834; KAS_I_II; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR000794; Beta-ketoacyl_synthase.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR11712:SF325; 3-OXOACYL-(ACYL-CARRIER-PROTEIN) SYNTHASE II FABF; 1.
DR PANTHER; PTHR11712; POLYKETIDE SYNTHASE-RELATED; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:GAC33406.1};
KW Fatty acid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00023160};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023160};
KW Transferase {ECO:0000256|RuleBase:RU003694, ECO:0000313|EMBL:GAC33406.1}.
FT DOMAIN 1..371
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
SQ SEQUENCE 415 AA; 44906 MW; ACA0159F0FFE09C6 CRC64;
MPEWDKYEGL NTRLGARVEN FTIPKHYSRK DLRSMGRVAQ LAVVSTENAL IDAGLLGHDI
LQSGMTGVAY GSSAGDTDAI ADFGNMLLHD DCDGLNANTY IKMMSHTSPV NIGVYFGLKG
RVYTTSSACT SASMGIGQAY EAIKFGQQTV MLAGGCEHLC ETEAAVFDTL YATSTMNETP
HLTPRPFDGA RDGLVIGEGA CTLVLEEYEH AIERGAEIYA ELIGFATNSD GSHITQPSSE
TMEKVIRLSL QDAGINPEDI GYVSAHGTAT SRGDIAESQA TAAVFGNKTP ISSLKSYTGH
TLGACGALEA WVGIEMMRND WFHPTANLQN VDENCGDLDY IKEEGRRLHI DYIMSNNFAF
GGLNTSHIKP SEMFAVSTII NILPTSTIHS TNIDLDECLG CNTRDRLLLR IYANN
//
