ID K6ZH87_9ALTE Unreviewed; 343 AA.
AC K6ZH87;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=DNA polymerase III subunit delta {ECO:0000256|ARBA:ARBA00017703};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN Name=holA {ECO:0000313|EMBL:GAC28278.1};
GN ORFNames=GPAL_1406 {ECO:0000313|EMBL:GAC28278.1};
OS Glaciecola pallidula DSM 14239 = ACAM 615.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Alteromonadaceae; Glaciecola.
OX NCBI_TaxID=1121922 {ECO:0000313|EMBL:GAC28278.1, ECO:0000313|Proteomes:UP000006251};
RN [1] {ECO:0000313|EMBL:GAC28278.1, ECO:0000313|Proteomes:UP000006251}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ACAM 615 {ECO:0000313|EMBL:GAC28278.1,
RC ECO:0000313|Proteomes:UP000006251};
RX PubMed=25009843;
RA Qin Q.-L., Xie B.-B., Yu Y., Shu Y.-L., Rong J.-C., Zhang Y.-J.,
RA Zhao D.-L., Chen X.-L., Zhang X.-Y., Chen B., Zhou B.-C., Zhang Y.-Z.;
RT "Comparative genomics of the marine bacterial genus Glaciecola reveals the
RT high degree of genomic diversity and genomic characteristic for cold
RT adaptation.";
RL Environ. Microbiol. 16:1642-1653(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase HolA subunit family.
CC {ECO:0000256|ARBA:ARBA00034754}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GAC28278.1}.
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DR EMBL; BAEQ01000023; GAC28278.1; -; Genomic_DNA.
DR RefSeq; WP_006010328.1; NZ_KE386815.1.
DR AlphaFoldDB; K6ZH87; -.
DR STRING; 1121922.GCA_000428905_00713; -.
DR OrthoDB; 9770982at2; -.
DR Proteomes; UP000006251; Unassembled WGS sequence.
DR GO; GO:0009360; C:DNA polymerase III complex; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd18138; HLD_clamp_pol_III_delta; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 1.20.272.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR008921; DNA_pol3_clamp-load_cplx_C.
DR InterPro; IPR032780; DNA_pol3_delt_C.
DR InterPro; IPR010372; DNA_pol3_delta_N.
DR InterPro; IPR005790; DNA_polIII_delta.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01128; holA; 1.
DR PANTHER; PTHR34388; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR PANTHER; PTHR34388:SF1; DNA POLYMERASE III SUBUNIT DELTA; 1.
DR Pfam; PF14840; DNA_pol3_delt_C; 1.
DR Pfam; PF06144; DNA_pol3_delta; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48019; post-AAA+ oligomerization domain-like; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000313|EMBL:GAC28278.1};
KW Transferase {ECO:0000313|EMBL:GAC28278.1}.
FT DOMAIN 22..190
FT /note="DNA polymerase III delta N-terminal"
FT /evidence="ECO:0000259|Pfam:PF06144"
FT DOMAIN 217..333
FT /note="DNA polymerase III subunit delta C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14840"
SQ SEQUENCE 343 AA; 38499 MW; E4D50157888A41A2 CRC64;
MQVYPNRFKQ HIQQQGLAPF MLVFGDEPQQ KLDMIDSIRA VAKSQGFDER QTLVADTDFS
WSQLIEATQT MSLFSDKQYI ELTLPTGKPG AEGSKVLTAI AENPSTDILI LIQGPKIGKD
VQKAKWFKAL DSQGIFSICY PLEGKQLVQW IEQRCRASQV NISPAGVNLL ADFSEGNLLA
AKQEIEKLAL VYADSGQQVN EKVLAAGMVD QSRFTVFQFV DDLLAGDIQK AIKILYRLES
EGVEPNIILW NLIKEAQTLA ECQAMQSLEG NINFTRLRIW QNKQVLYQNA LRRLTPSHIS
LLNTHLQQAD LILKSETTAR PYILLSHLAL LFLPAPLQNM SLN
//
