ID K6ZM15_PANTR Unreviewed; 179 AA.
AC K6ZM15; A0A2J8PYQ6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Optic atrophy 3 (Autosomal recessive, with chorea and spastic paraplegia) {ECO:0000313|EMBL:JAA05956.1};
DE SubName: Full=Outer mitochondrial membrane lipid metabolism regulator OPA3 {ECO:0000313|Ensembl:ENSPTRP00000068483.1};
GN Name=OPA3 {ECO:0000313|EMBL:JAA05956.1,
GN ECO:0000313|Ensembl:ENSPTRP00000068483.1,
GN ECO:0000313|VGNC:VGNC:58018};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA05956.1};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000068483.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA05956.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA05956.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA41585.1}, Skin {ECO:0000313|EMBL:JAA27241.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA18434.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000068483.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May play some role in mitochondrial processes.
CC {ECO:0000256|ARBA:ARBA00003027}.
CC -!- SIMILARITY: Belongs to the OPA3 family.
CC {ECO:0000256|ARBA:ARBA00007584}.
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DR EMBL; AC192266; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01005382; JAA05956.1; -; mRNA.
DR EMBL; GABF01003711; JAA18434.1; -; mRNA.
DR EMBL; GABD01005859; JAA27241.1; -; mRNA.
DR EMBL; GABE01003154; JAA41585.1; -; mRNA.
DR RefSeq; XP_016791714.1; XM_016936225.1.
DR Ensembl; ENSPTRT00000089641.1; ENSPTRP00000068483.1; ENSPTRG00000045719.1.
DR VGNC; VGNC:58018; OPA3.
DR GeneTree; ENSGT00390000009795; -.
DR OrthoDB; 5316632at2759; -.
DR Proteomes; UP000002277; Chromosome 19.
DR Bgee; ENSPTRG00000045719; Expressed in lung and 21 other cell types or tissues.
DR InterPro; IPR010754; OPA3-like.
DR PANTHER; PTHR12499:SF0; OPTIC ATROPHY 3 PROTEIN; 1.
DR PANTHER; PTHR12499; OPTIC ATROPHY 3 PROTEIN OPA3; 1.
DR Pfam; PF07047; OPA3; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
SQ SEQUENCE 179 AA; 19987 MW; 02B48F84B24E5AFF CRC64;
MVVGAFPMAK LLYLGIRQVS KPLANRIKEA ARRSEFFKTY ICLPPAQLYH WVEMRTKMRI
MGFRGTVIKP LNEEAAAELG AELLGEATIF IVGGGCLVLE YWRHQAQQRH KEEEQRAAWN
ALRDEVGHLA LALEALQAQV QAAPPQGALE ELRTELQEVR AQLCNPGRSA SQAVPASKK
//
