ID   K7ADU4_9ALTE            Unreviewed;      1037 AA.
AC   K7ADU4;
DT   09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT   09-JAN-2013, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Acriflavin resistance protein {ECO:0000313|EMBL:AGH43107.1};
GN   ORFNames=C427_0998 {ECO:0000313|EMBL:AGH43107.1};
OS   Paraglaciecola psychrophila 170.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Paraglaciecola.
OX   NCBI_TaxID=1129794 {ECO:0000313|EMBL:AGH43107.1, ECO:0000313|Proteomes:UP000011864};
RN   [1] {ECO:0000313|EMBL:AGH43107.1, ECO:0000313|Proteomes:UP000011864}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=170 {ECO:0000313|EMBL:AGH43107.1,
RC   ECO:0000313|Proteomes:UP000011864};
RX   PubMed=23640379;
RA   Yin J., Chen J., Liu G., Yu Y., Song L., Wang X., Qu X.;
RT   "Complete Genome Sequence of Glaciecola psychrophila Strain 170T.";
RL   Genome Announc. 1:E00199-13(2013).
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DR   EMBL; CP003837; AGH43107.1; -; Genomic_DNA.
DR   RefSeq; WP_007640248.1; NZ_BAES01000064.1.
DR   AlphaFoldDB; K7ADU4; -.
DR   STRING; 1129794.C427_0998; -.
DR   KEGG; gps:C427_0998; -.
DR   PATRIC; fig|1129794.4.peg.986; -.
DR   eggNOG; COG0841; Bacteria.
DR   HOGENOM; CLU_002755_1_2_6; -.
DR   OrthoDB; 9757904at2; -.
DR   Proteomes; UP000011864; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF14; BLL4319 PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000011864};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..34
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        334..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        386..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        431..451
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        852..871
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        878..898
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        950..969
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        981..1007
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1037 AA;  113611 MW;  D4D507DBAD2A091C CRC64;
     MFLSDISVKR PVFASVVNLL LVVFGIVSIS LLSLREYPDI DPPIVSINTN YPGASASIVE
     TRITQLIEER ISGIEGIKNI ESSSRNGRSS ISIEFDLSRD IDAASNDVRE RVSRVLNNLP
     DQAEPPEVSK SNSDEDVIVW YNLRSDNLSV MELTDYADRF VVDRLSVAEG VARVQLGGGR
     KYAMKVWLDR NAMAARDITV TDIENVIRSE NVELPAGEVE SIDRDFEVRV ARSFLTPEDF
     SNLTIKASAD GYLVKLKEVA RVELGAEDDE TEFRGGGVNM IGLGIVKQSK ANTLEVARAA
     KAAIQLIEQT LPDNIFIVPS YDSSVFIEAS INEVYETLAI AILMVVLVIY VFLGNIRATL
     IPAVTVPVSL VSAFIVMYAL GFSINLLTLL AMVLAIGLVV DDAIVVLENI SRRIEMGEPP
     ILAAYRGARE VGFAVIATTL VLISVFVPLV FLQGNIGRLF TEFALAIAAA VAFSSVTALT
     LSPMMCSKLL KKRSKPSGFA HWVDNKFRKI EQGYFTGLGT TLHQPWLMSL LVIGSIVALF
     KLIQILPGEF VPKEDRGNFF ILMQSAEGSS FESNAANLKK IESILLPYTE TGEADRIIVR
     TPGFGGNAGI AIVGTPIGPE KKGSTFDLMD EISGKLVNIP DVTAFAVMRS GIGGRGLGRP
     VQFVLQGNTY EELVEWRDIV LTKARENPNL IRIDSDYKET WPQLLVNIDK NRAADLGVSI
     SDIGRTLETM LGQRRVSTFL DKGQEYDVIM EGWEEDYRSP SSIENIYVRS SQSNQLIPLD
     NLLTVGENAT SSRLNRYNRM RSITISANLA DGYTVGEALD YLRNIVDTEL PAEVAIDYKG
     ESQQYQDSGS SILFIFVLAL AITYLVLAAQ FENWIQPLVI MLTVPLALVG AFIGLYFSDM
     TLNIYSQIGL VMLIGLAAKN GILIVEFANQ LRDAGVEFEK ALRQAATQRL RPIVMTGFTT
     IFSSLPLVLA TGAGAESRTV IGMVIFAGVT VSAFLTLYVV PTAYYLLARN TGSPNARAQM
     IASLEKTIEY KKGDLDI
//