ID K7CT92_PANTR Unreviewed; 400 AA.
AC K7CT92; A0A2J8NQ59;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Leucine-rich repeat flightless-interacting protein 2 {ECO:0000256|ARBA:ARBA00040512};
GN Name=LRRFIP2 {ECO:0000313|EMBL:JAA35923.1,
GN ECO:0000313|Ensembl:ENSPTRP00000075367.1,
GN ECO:0000313|VGNC:VGNC:14626};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA35923.1};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000075367.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA35923.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA02960.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA35923.1}, Skin {ECO:0000313|EMBL:JAA32573.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA16070.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000075367.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the LRRFIP family.
CC {ECO:0000256|ARBA:ARBA00008275}.
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DR EMBL; AACZ04000224; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04000225; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04000226; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01008378; JAA02960.1; -; mRNA.
DR EMBL; GABF01006075; JAA16070.1; -; mRNA.
DR EMBL; GABD01000527; JAA32573.1; -; mRNA.
DR EMBL; GABE01008816; JAA35923.1; -; mRNA.
DR RefSeq; XP_001170841.1; XM_001170841.4.
DR Ensembl; ENSPTRT00000086482.1; ENSPTRP00000075367.1; ENSPTRG00000014745.6.
DR GeneID; 470788; -.
DR KEGG; ptr:470788; -.
DR CTD; 9209; -.
DR VGNC; VGNC:14626; LRRFIP2.
DR GeneTree; ENSGT00530000063564; -.
DR OrthoDB; 5363471at2759; -.
DR Proteomes; UP000002277; Chromosome 3.
DR Bgee; ENSPTRG00000014745; Expressed in fibroblast and 21 other cell types or tissues.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.20.5.4090; -; 1.
DR InterPro; IPR019139; LRRFIP1/2.
DR PANTHER; PTHR19212; LEUCINE RICH REPEAT IN FLII INTERACTING PROTEIN; 1.
DR PANTHER; PTHR19212:SF6; LEUCINE-RICH REPEAT FLIGHTLESS-INTERACTING PROTEIN 2; 1.
DR Pfam; PF09738; LRRFIP; 1.
PE 2: Evidence at transcript level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REGION 53..119
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 249..392
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 53..69
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..110
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 45400 MW; 3C144D0C95E4E1D7 CRC64;
MGTPGSGRKR TPVKDRFSAE DEALSNIARE AEARLAAKRA ARAEARDIRM RELERQQKEL
DEKSDKQYAE NYTRPSSRNS ASATTPLSGN SSRRGSGDTS SLIDPDTSLS ELRESLSEVE
EKYKKAMVSN AQLDNEKNNL IYQVDTLKDV IEEQEEQMAE FYRENEEKSK ELERQKHMCS
VLQHKMEELK EGLRQRDELI EKHGLVIIPD GTPNGDVSHE PVAGAITVVS QEAAQVLESA
GEGPLDVRLR KLAGEKEELL SQIRKLKLQL EEERQKCSRN DGTVGDLAGL QNGSDLQFIE
MQRDANRQIS EYKFKLSKAE QDITTLEQSI SRLEGQVLRY KTAAENAEKV EDELKAEKRK
LQRELRTALD KIEEMEMTNS HLAKRLEKMK ANRTALLAQQ
//
