ID K7D0J1_PANTR Unreviewed; 444 AA.
AC K7D0J1; A0A2J8JXN3;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Sushi repeat containing protein X-linked {ECO:0000313|Ensembl:ENSPTRP00000063442.1};
DE SubName: Full=Sushi-repeat containing protein, X-linked {ECO:0000313|EMBL:JAA25647.1};
GN Name=SRPX {ECO:0000313|EMBL:JAA25647.1,
GN ECO:0000313|Ensembl:ENSPTRP00000063442.1, ECO:0000313|VGNC:VGNC:8307};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA25647.1};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000063442.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA25647.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Skin {ECO:0000313|EMBL:JAA25647.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000063442.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR EMBL; AACZ04032787; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC193046; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABD01007453; JAA25647.1; -; mRNA.
DR RefSeq; XP_016799388.1; XM_016943899.1.
DR Ensembl; ENSPTRT00000090415.1; ENSPTRP00000063442.1; ENSPTRG00000021796.6.
DR VGNC; VGNC:8307; SRPX.
DR GeneTree; ENSGT00940000160302; -.
DR OrthoDB; 5406861at2759; -.
DR Proteomes; UP000002277; Chromosome X.
DR Bgee; ENSPTRG00000021796; Expressed in fibroblast and 19 other cell types or tissues.
DR CDD; cd00033; CCP; 3.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 3.
DR InterPro; IPR025232; DUF4174.
DR InterPro; IPR003410; HYR_dom.
DR InterPro; IPR043555; SRPX-like.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR46343; HYR DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46343:SF1; SUSHI REPEAT-CONTAINING PROTEIN SRPX; 1.
DR Pfam; PF13778; DUF4174; 1.
DR Pfam; PF02494; HYR; 1.
DR Pfam; PF00084; Sushi; 3.
DR SMART; SM00032; CCP; 3.
DR SUPFAM; SSF57535; Complement control module/SCR domain; 3.
DR PROSITE; PS50825; HYR; 1.
DR PROSITE; PS50923; SUSHI; 3.
PE 2: Evidence at transcript level;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00302}; Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Sushi {ECO:0000256|ARBA:ARBA00022659, ECO:0000256|PROSITE-
KW ProRule:PRU00302}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..444
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015095946"
FT DOMAIN 47..97
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 98..156
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DOMAIN 155..239
FT /note="HYR"
FT /evidence="ECO:0000259|PROSITE:PS50825"
FT DOMAIN 240..299
FT /note="Sushi"
FT /evidence="ECO:0000259|PROSITE:PS50923"
FT DISULFID 127..154
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
FT DISULFID 270..297
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00302"
SQ SEQUENCE 444 AA; 49382 MW; 369E18F51CECE377 CRC64;
MGSPAHRPAL LLLLPPLLLL LLLRVPPSRS FPDTPWCSPI KVKYGDVYCR APQGGYYKTA
LGTRCDIRCQ KGYELHGSSL LICQSNKRWS DKVICKQKRC PTLAMPANGG FKCVDGAYFN
SRCEYYCSPG YTLKGERTVT CMDNKAWSGR PASCVDMEPP RIKCPSVKER IAEPNKLTVR
VSWETPEGRD TADGILTDVI LKGLPPGSNF PEGDHKIQYT VYDRAENKGT CKFRVKVRVK
RCGKLNAPEN GYMKCSSDGD NYGATCEFSC IGGYELQGSP ARVCQSNLAW SGTEPTCAAM
NVNVGVRTAA ALLDQFYEKR RLLIVSTPTA RNLLYRLQLG MLQQAQCGLD LRHITVVELV
GVFPTLIGRI GAKIMPPALA LQLRLLLRIP LYSFSMVLVD KHGMDKERYV SLVMPVALFN
LIDTFPLRKE EMVLQAEMSQ TCNT
//
