ID K7D3A7_PANTR Unreviewed; 520 AA.
AC K7D3A7; A0A2J8NM49; H2QHE6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 09-JAN-2013, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Membrane bound O-acyltransferase domain containing 2 {ECO:0000313|EMBL:JAA26922.1, ECO:0000313|Ensembl:ENSPTRP00000020007.3};
GN Name=MBOAT2 {ECO:0000313|EMBL:JAA26922.1,
GN ECO:0000313|Ensembl:ENSPTRP00000020007.3,
GN ECO:0000313|VGNC:VGNC:10742};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|EMBL:JAA26922.1};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000020007.3, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|EMBL:JAA26922.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Adipose stromal {ECO:0000313|EMBL:JAA09137.1}, Skeletal muscle
RC {ECO:0000313|EMBL:JAA43583.1}, Skin {ECO:0000313|EMBL:JAA26922.1}, and
RC Smooth vascular {ECO:0000313|EMBL:JAA22085.1};
RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.;
RT "De novo assembly of the reference chimpanzee transcriptome from NextGen
RT mRNA sequences.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000020007.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACZ04027951; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; GABC01002201; JAA09137.1; -; mRNA.
DR EMBL; GABC01002200; JAA09138.1; -; mRNA.
DR EMBL; GABC01002199; JAA09139.1; -; mRNA.
DR EMBL; GABC01002198; JAA09140.1; -; mRNA.
DR EMBL; GABC01002197; JAA09141.1; -; mRNA.
DR EMBL; GABC01002196; JAA09142.1; -; mRNA.
DR EMBL; GABF01000060; JAA22085.1; -; mRNA.
DR EMBL; GABD01006179; JAA26921.1; -; mRNA.
DR EMBL; GABD01006178; JAA26922.1; -; mRNA.
DR EMBL; GABD01006177; JAA26923.1; -; mRNA.
DR EMBL; GABD01006176; JAA26924.1; -; mRNA.
DR EMBL; GABD01006175; JAA26925.1; -; mRNA.
DR EMBL; GABD01006174; JAA26926.1; -; mRNA.
DR EMBL; GABE01001156; JAA43583.1; -; mRNA.
DR EMBL; GABE01001155; JAA43584.1; -; mRNA.
DR RefSeq; XP_016802206.1; XM_016946717.1.
DR STRING; 9598.ENSPTRP00000020007; -.
DR PaxDb; 9598-ENSPTRP00000020007; -.
DR Ensembl; ENSPTRT00000021683.3; ENSPTRP00000020007.3; ENSPTRG00000011634.4.
DR GeneID; 459013; -.
DR KEGG; ptr:459013; -.
DR CTD; 129642; -.
DR VGNC; VGNC:10742; MBOAT2.
DR eggNOG; KOG2704; Eukaryota.
DR GeneTree; ENSGT01030000234564; -.
DR OMA; ASWPIRF; -.
DR OrthoDB; 5297955at2759; -.
DR TreeFam; TF314906; -.
DR Proteomes; UP000002277; Chromosome 2A.
DR Bgee; ENSPTRG00000011634; Expressed in bone marrow and 21 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IBA:GO_Central.
DR GO; GO:0047184; F:1-acylglycerophosphocholine O-acyltransferase activity; IEA:Ensembl.
DR GO; GO:0106262; F:1-acylglycerophosphoethanolamine O-acyltransferase activity; IEA:Ensembl.
DR GO; GO:0106263; F:1-acylglycerophosphoserine O-acyltransferase activity; IEA:Ensembl.
DR GO; GO:0016746; F:acyltransferase activity; IBA:GO_Central.
DR GO; GO:0030258; P:lipid modification; IBA:GO_Central.
DR GO; GO:0036151; P:phosphatidylcholine acyl-chain remodeling; IEA:Ensembl.
DR GO; GO:0036152; P:phosphatidylethanolamine acyl-chain remodeling; IEA:Ensembl.
DR GO; GO:0036150; P:phosphatidylserine acyl-chain remodeling; IEA:Ensembl.
DR InterPro; IPR004299; MBOAT_fam.
DR PANTHER; PTHR13906:SF7; LYSOPHOSPHOLIPID ACYLTRANSFERASE 2; 1.
DR PANTHER; PTHR13906; PORCUPINE; 1.
DR Pfam; PF03062; MBOAT; 1.
PE 2: Evidence at transcript level;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000313|EMBL:JAA26922.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:JAA26922.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 26..46
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 58..81
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 366..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 412..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 520 AA; 59499 MW; E635DEFDA140397C CRC64;
MATTSTTGST LLQPLSNAVQ LPIDQVNFVV CQLFALLAAI WFRTYLHSSK TSSFIRHVVA
TLLGLYLALF CFGWYALHFL VQSGISYCIM IIIGVENMHN YCFVFALGYL TVCQVTRVYI
FDYGQYSADF SGPMMIITQK ITSLACEIHD GMFRKDEELT SSQRDLAVRR MPSLLEYLSY
NCNFMGILAG PLCSYKDYIT FIEGRSYHIT QSGENGKEET QYEKTEPSPN TAVVQKLLVC
GLSLLFHLTI CTTLPVEYNI DEHFQATASW PTKIIYLYIS LLAARPKYYF AWTLADAINN
AAGFGFRGYD ENGAARWDLI SNLRIQQIEM STSFKMFLDN WNIQTALWLK RVCYERTSFS
PTIQTFILSA IWHGVYPGYY LTFLTGVLMT LAARAMRNNF RHYFVEPSQL KLFYDVITWI
VTQVAISYTV VPFVLLSVKP SLTFYSSWYY CLHILGILVL LLLPVKKTQR RKNTHENIQL
SQSKKFDEGE NSLGRNSFST TNNVCNQNQE IASRHSSLKQ
//
