ID K7E4K6_MONDO Unreviewed; 326 AA.
AC K7E4K6;
DT 09-JAN-2013, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 51.
DE RecName: Full=L1 transposable element RRM domain-containing protein {ECO:0008006|Google:ProtNLM};
OS Monodelphis domestica (Gray short-tailed opossum).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Monodelphis.
OX NCBI_TaxID=13616 {ECO:0000313|Ensembl:ENSMODP00000040708.2, ECO:0000313|Proteomes:UP000002280};
RN [1] {ECO:0000313|Ensembl:ENSMODP00000040708.2, ECO:0000313|Proteomes:UP000002280}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17495919; DOI=10.1038/nature05805;
RA Mikkelsen T.S., Wakefield M.J., Aken B., Amemiya C.T., Chang J.L., Duke S.,
RA Garber M., Gentles A.J., Goodstadt L., Heger A., Jurka J., Kamal M.,
RA Mauceli E., Searle S.M., Sharpe T., Baker M.L., Batzer M.A., Benos P.V.,
RA Belov K., Clamp M., Cook A., Cuff J., Das R., Davidow L., Deakin J.E.,
RA Fazzari M.J., Glass J.L., Grabherr M., Greally J.M., Gu W., Hore T.A.,
RA Huttley G.A., Kleber M., Jirtle R.L., Koina E., Lee J.T., Mahony S.,
RA Marra M.A., Miller R.D., Nicholls R.D., Oda M., Papenfuss A.T., Parra Z.E.,
RA Pollock D.D., Ray D.A., Schein J.E., Speed T.P., Thompson K.,
RA VandeBerg J.L., Wade C.M., Walker J.A., Waters P.D., Webber C.,
RA Weidman J.R., Xie X., Zody M.C., Baldwin J., Abdouelleil A., Abdulkadir J.,
RA Abebe A., Abera B., Abreu J., Acer S.C., Aftuck L., Alexander A., An P.,
RA Anderson E., Anderson S., Arachi H., Azer M., Bachantsang P., Barry A.,
RA Bayul T., Berlin A., Bessette D., Bloom T., Bloom T., Boguslavskiy L.,
RA Bonnet C., Boukhgalter B., Bourzgui I., Brown A., Cahill P., Channer S.,
RA Cheshatsang Y., Chuda L., Citroen M., Collymore A., Cooke P., Costello M.,
RA D'Aco K., Daza R., De Haan G., DeGray S., DeMaso C., Dhargay N., Dooley K.,
RA Dooley E., Doricent M., Dorje P., Dorjee K., Dupes A., Elong R., Falk J.,
RA Farina A., Faro S., Ferguson D., Fisher S., Foley C.D., Franke A.,
RA Friedrich D., Gadbois L., Gearin G., Gearin C.R., Giannoukos G., Goode T.,
RA Graham J., Grandbois E., Grewal S., Gyaltsen K., Hafez N., Hagos B.,
RA Hall J., Henson C., Hollinger A., Honan T., Huard M.D., Hughes L.,
RA Hurhula B., Husby M.E., Kamat A., Kanga B., Kashin S., Khazanovich D.,
RA Kisner P., Lance K., Lara M., Lee W., Lennon N., Letendre F., LeVine R.,
RA Lipovsky A., Liu X., Liu J., Liu S., Lokyitsang T., Lokyitsang Y.,
RA Lubonja R., Lui A., MacDonald P., Magnisalis V., Maru K., Matthews C.,
RA McCusker W., McDonough S., Mehta T., Meldrim J., Meneus L., Mihai O.,
RA Mihalev A., Mihova T., Mittelman R., Mlenga V., Montmayeur A., Mulrain L.,
RA Navidi A., Naylor J., Negash T., Nguyen T., Nguyen N., Nicol R., Norbu C.,
RA Norbu N., Novod N., O'Neill B., Osman S., Markiewicz E., Oyono O.L.,
RA Patti C., Phunkhang P., Pierre F., Priest M., Raghuraman S., Rege F.,
RA Reyes R., Rise C., Rogov P., Ross K., Ryan E., Settipalli S., Shea T.,
RA Sherpa N., Shi L., Shih D., Sparrow T., Spaulding J., Stalker J.,
RA Stange-Thomann N., Stavropoulos S., Stone C., Strader C., Tesfaye S.,
RA Thomson T., Thoulutsang Y., Thoulutsang D., Topham K., Topping I.,
RA Tsamla T., Vassiliev H., Vo A., Wangchuk T., Wangdi T., Weiand M.,
RA Wilkinson J., Wilson A., Yadav S., Young G., Yu Q., Zembek L., Zhong D.,
RA Zimmer A., Zwirko Z., Jaffe D.B., Alvarez P., Brockman W., Butler J.,
RA Chin C., Gnerre S., MacCallum I., Graves J.A., Ponting C.P., Breen M.,
RA Samollow P.B., Lander E.S., Lindblad-Toh K.;
RT "Genome of the marsupial Monodelphis domestica reveals innovation in non-
RT coding sequences.";
RL Nature 447:167-177(2007).
RN [2] {ECO:0000313|Ensembl:ENSMODP00000040708.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; K7E4K6; -.
DR Ensembl; ENSMODT00000043814.2; ENSMODP00000040708.2; ENSMODG00000037316.1.
DR eggNOG; ENOG502SRQ0; Eukaryota.
DR GeneTree; ENSGT01050000244818; -.
DR HOGENOM; CLU_062834_0_2_1; -.
DR InParanoid; K7E4K6; -.
DR TreeFam; TF335236; -.
DR Proteomes; UP000002280; Chromosome 1.
DR Bgee; ENSMODG00000037316; Expressed in extraembryonic membrane and 11 other cell types or tissues.
DR GO; GO:1990904; C:ribonucleoprotein complex; IBA:GO_Central.
DR GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR GO; GO:0032197; P:retrotransposition; IBA:GO_Central.
DR Gene3D; 3.30.250.20; L1 transposable element, C-terminal domain; 1.
DR Gene3D; 3.30.70.1820; L1 transposable element, RRM domain; 1.
DR InterPro; IPR042566; L1_C.
DR InterPro; IPR035300; L1_dsRBD.
DR InterPro; IPR043636; L1_RRM_dom.
DR InterPro; IPR004244; Transposase_22.
DR PANTHER; PTHR11505; L1 TRANSPOSABLE ELEMENT-RELATED; 1.
DR PANTHER; PTHR11505:SF210; TRANSPOSASE_22 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF17490; Tnp_22_dsRBD; 1.
DR Pfam; PF02994; Transposase_22; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002280}.
FT DOMAIN 155..251
FT /note="L1 transposable element RRM"
FT /evidence="ECO:0000259|Pfam:PF02994"
FT DOMAIN 254..312
FT /note="L1 transposable element dsRBD-like"
FT /evidence="ECO:0000259|Pfam:PF17490"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 69..152
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 326 AA; 38215 MW; 957F1490DB9810DF CRC64;
MAHMAQNQAS RKKGKKVTIE NFYGGSTQGK ENEEEIQKNS EHASQNGNYQ QALEDLKLEL
IQKMETFWKE KWEKEISCLT DKTAQLEKEL EASNRRADKA EKQIQSLMTR IKHLEESEMI
KQQESIKQTQ IINELEENRK YLTEKVTDLE NRGRRENLRI IGLPEKPEVN NKLDIILEEI
IKENCPHVLE QGGKIEIERI HRTPSILNPQ KTTPRNVIAK FKSFQVKEKI LQEAKKKSFR
YKGAPIRITH DLAANTLRDR KAWNTIFRKA RELGLQPRIN YPAKLTIYFQ GKVWAFNKIE
DFQAFAKKRP ELCGKFDIQA QKARET
//
